Reactome | MST4 [cytosol]

MST4 [cytosol]

Stable Identifier

R-HSA-351918

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

MASK

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9P289 STK26

Gene Names

STK26, MASK, MST4

Chain

initiator methionine:1, chain:2-416

Reference Genes

BioGPS Gene:51765 STK26

CTD Gene:51765 STK26

dbSNP Gene:51765 STK26

ENSEMBL:ENSG00000134602 STK26

HGNC:18174 STK26

KEGG Gene (Homo sapiens):51765 STK26

Monarch:51765 STK26

NCBI Gene:51765 STK26

OMIM:300547 STK26

UCSC:Q9P289 STK26

Reference Transcript

Other Identifiers

0005390050

11720115_a_at

11720116_a_at

11741309_x_at

11747272_a_at

17106997

218499_at

224407_s_at

3991113

3991114

3991115

3991116

3991117

3991126

3991129

3991131

3991132

3991133

3991135

3991136

3991138

3991139

3991141

3991142

3991143

3991145

3991146

43456_at

51765

54316_at

8169949

A_14_P113118

A_23_P32414

GE53978

GO:0000139

GO:0000166

GO:0000278

GO:0000287

GO:0003674

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005794

GO:0005798

GO:0005829

GO:0005886

GO:0006464

GO:0006468

GO:0006915

GO:0006950

GO:0007049

GO:0007165

GO:0007346

GO:0008150

GO:0008219

GO:0009267

GO:0012506

GO:0016020

GO:0016301

GO:0016310

GO:0016324

GO:0016740

GO:0022607

GO:0023014

GO:0030033

GO:0030336

GO:0031098

GO:0031410

GO:0032147

GO:0040011

GO:0042542

GO:0042802

GO:0042803

GO:0042981

GO:0043167

GO:0043226

GO:0046777

GO:0046872

GO:0048471

GO:0048870

GO:0070062

GO:0071944

GO:1903205

ILMN_1676159

ILMN_2328776

PH_hs_0002081

TC0X000628.hg

g13549066_3p_s_at

g7706568_3p_at

Participant Of

input

Caspase-mediated cleavage of MASK

Other forms of this molecule

MST4(306-416) [cytosol]

MST4(1-305) [cytosol]

Inferred To

KIC1 [cytosol] (Saccharomyces cerevisiae)

MST4 [cytosol] (Bos taurus)

MST4 [cytosol] (Dictyostelium discoideum)

MST4 [cytosol] (Sus scrofa)

Stk26 [cytosol] (Mus musculus)

Stk26 [cytosol] (Rattus norvegicus)

Homologues of MST4 [cytosol] (Caenorhabditis elegans)

Homologues of MST4 [cytosol] (Dictyostelium discoideum)

Homologues of MST4 [cytosol] (Schizosaccharomyces pombe)

sid1 [cytosol] (Schizosaccharomyces pombe)

mes-1 [cytosol] (Caenorhabditis elegans)

STK26 [cytosol] (Canis familiaris)

STK26 [cytosol] (Gallus gallus)

gck-1 [cytosol] (Caenorhabditis elegans)

ppk2 [cytosol] (Schizosaccharomyces pombe)

nak1 [cytosol] (Schizosaccharomyces pombe)

svkA [cytosol] (Dictyostelium discoideum)

stk26 [cytosol] (Danio rerio)

stk26 [cytosol] (Xenopus tropicalis)

GckIII [cytosol] (Drosophila melanogaster)

ppk11 [cytosol] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_057626.2, NP_001035917.1, NP_001035918.1

ZINC - World Drugs

STK26_HUMAN

OpenTargets

ENSG00000134602

ZINC - FDA approved

STK26_HUMAN

ZINC - Substances

STK26_HUMAN

ZINC - Biogenic

STK26_HUMAN

ZINC target

Q9P289

PRO

Q9P289

PDB

3GGF, 4GEH, 3W8I, 4FZA, 4FZF, 4FZD, 5YF4, 5XY9

ZINC - Investigational

STK26_HUMAN

IntEnz

2.7.11.1

GeneCards

Q9P289

HPA

ENSG00000134602-STK26

Ensembl

ENST00000394334, ENST00000394335, ENSG00000134602, ENSP00000419702, ENSP00000377868, ENST00000496850, ENSP00000377867

ZINC - Predictions - Purchasable

STK26_HUMAN

HMDB Protein

HMDBP08763

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BUL8 PDC10			0.818	7
UniProt:Q13033 STRN3			0.737	6
UniProt:O43815 STRN	3	STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673902) STRN [cytosol] (R-HSA-9037081) p-11Y STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673908)	0.708	4
UniProt:Q9Y3A3 PHOCN			0.69	4
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.682	5
UniProt:Q9P2B4 CT2NL			0.662	4
UniProt:P30153 PPP2R1A	2	PPP2R1A [nucleoplasm] (R-HSA-165968) PPP2R1A [cytosol] (R-HSA-165982)	0.643	3
UniProt:Q14BN4 SLMAP			0.643	3
UniProt:Q8WZ74 CTTB2			0.597	3
UniProt:Q9P289 STK26	3	MST4 [cytosol] (R-HSA-351918) MST4(306-416) [cytosol] (R-HSA-351903) MST4(1-305) [cytosol] (R-HSA-351855)	0.593	4
UniProt:Q9Y376 CAB39	4	CAB39 [extracellular region] (R-HSA-6806462) CAB39 [ficolin-1-rich granule lumen] (R-HSA-6801287) CAB39 [secretory granule lumen] (R-HSA-6801288) CAB39 [cytosol] (R-HSA-380969)	0.544	6
UniProt:P67775 PPP2CA	4	PPP2CA [nucleoplasm] (R-HSA-165978) PPP2CA [cytosol] (R-HSA-165971) MeL-PPP2CA [nucleoplasm] (R-HSA-8857791) p-Y307-PPP2CA [cytosol] (R-HSA-8857939)	0.527	2
UniProt:Q9NRL3 STRN4			0.527	2
UniProt:O00506 STK25			0.527	3
UniProt:Q9Y6E0 STK24	4	STK24(314-443) [cytosol] (R-HSA-351898) STK24(1-313) [nucleoplasm] (R-HSA-351944) STK24(1-313) [cytosol] (R-HSA-351892) STK24 [cytosol] (R-HSA-351829)	0.527	2
UniProt:Q5VSL9 STRP1			0.499	2

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