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MST4 [cytosol]
Stable Identifier
R-HSA-351918
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MASK
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Apoptotic execution phase (Homo sapiens)
Apoptotic cleavage of cellular proteins (Homo sapiens)
Caspase-mediated cleavage of MASK (Homo sapiens)
MST4 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9P289 STK26
Gene Names
STK26, MASK, MST4
Chain
initiator methionine:1, chain:2-416
Reference Genes
BioGPS Gene:51765 STK26
COSMIC (genes):STK26 STK26
CTD Gene:51765 STK26
dbSNP Gene:51765 STK26
ENSEMBL:ENSG00000134602 STK26
HGNC:18174 STK26
KEGG Gene (Homo sapiens):51765 STK26
Monarch:51765 STK26
NCBI Gene:51765 STK26
OMIM:300547 STK26
UCSC:Q9P289 STK26
Reference Transcript
RefSeq:NM_016542.3 STK26
RefSeq:NM_001042453.1 STK26
RefSeq:NM_001042452.1 STK26
Other Identifiers
0005390050
11720115_a_at
11720116_a_at
11741309_x_at
11747272_a_at
17106997
218499_PM_at
218499_at
224407_PM_s_at
224407_s_at
3991113
3991114
3991115
3991116
3991117
3991126
3991129
3991131
3991132
3991133
3991135
3991136
3991138
3991139
3991141
3991142
3991143
3991145
3991146
43456_at
51765
54316_at
8169949
A_14_P113118
A_23_P32414
GE53978
GO:0000166
GO:0000287
GO:0003674
GO:0004672
GO:0004674
GO:0004712
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005794
GO:0005798
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006915
GO:0006950
GO:0008150
GO:0008219
GO:0009267
GO:0012506
GO:0016020
GO:0016301
GO:0016310
GO:0016324
GO:0016740
GO:0022607
GO:0030033
GO:0030336
GO:0031410
GO:0040011
GO:0042542
GO:0042802
GO:0042803
GO:0042981
GO:0043167
GO:0043226
GO:0046777
GO:0046872
GO:0048471
GO:0048870
GO:0070062
GO:0071944
GO:0106310
GO:1903205
HMNXSV003027586
ILMN_1676159
ILMN_2328776
PH_hs_0002081
TC0X000628.hg
g13549066_3p_s_at
g7706568_3p_at
Participates
as an input of
Caspase-mediated cleavage of MASK (Homo sapiens)
Other forms of this molecule
MST4(306-416) [cytosol]
MST4(1-305) [cytosol]
Inferred To
gck-1 [cytosol]
(Caenorhabditis elegans)
KIC1 [cytosol]
(Saccharomyces cerevisiae)
MST4 [cytosol]
(Dictyostelium discoideum)
Stk26 [cytosol]
(Mus musculus)
Stk26 [cytosol]
(Rattus norvegicus)
nak1 [cytosol]
(Schizosaccharomyces pombe)
svkA [cytosol]
(Dictyostelium discoideum)
stk26 [cytosol]
(Danio rerio)
stk26 [cytosol]
(Xenopus tropicalis)
Homologues of MST4 [cytosol]
(Dictyostelium discoideum)
Homologues of MST4 [cytosol]
(Schizosaccharomyces pombe)
GckIII [cytosol]
(Drosophila melanogaster)
ppk11 [cytosol]
(Schizosaccharomyces pombe)
sid1 [cytosol]
(Schizosaccharomyces pombe)
STK26 [cytosol]
(Bos taurus)
STK26 [cytosol]
(Canis familiaris)
STK26 [cytosol]
(Gallus gallus)
STK26 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001035917.1
,
NP_057626.2
,
NP_001035918.1
ZINC - World Drugs
STK26_HUMAN
Guide to Pharmacology - Targets
2287
OpenTargets
ENSG00000134602
ZINC - FDA approved
STK26_HUMAN
ZINC - Substances
STK26_HUMAN
ZINC - Biogenic
STK26_HUMAN
ZINC target
Q9P289
PRO
Q9P289
PDB
5XY9
,
3W8I
,
4GEH
,
4FZF
,
5YF4
,
4FZA
,
4FZD
,
7B36
,
3GGF
GeneCards
Q9P289
HPA
ENSG00000134602-STK26
Ensembl
ENSP00000377868
,
ENSP00000377867
,
ENST00000496850
,
ENST00000394334
,
ENSG00000134602
,
ENST00000394335
,
ENSP00000419702
Pharos - Targets
Q9P289
ZINC - Predictions - Purchasable
STK26_HUMAN
HMDB Protein
HMDBP08763
Interactors (19)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BUL8 PDC10
0.86
8
UniProt:Q13033 STRN3
0.794
7
UniProt:O43815 STRN
5
STRN [cytosol]
(R-HSA-9037081)
STRN(1-265)-PDGFRA(580-1089) fusion [cytosol]
(R-HSA-9673902)
p-11Y STRN(1-265)-PDGFRA(580-1089) fusion [cytosol]
(R-HSA-9673908)
STRN(1-137)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9700485)
STRN(1-137)-p-7Y ALK(1058-1620) fusion [cytosol]
(R-HSA-9700467)
0.773
5
UniProt:Q9Y3A3 PHOCN
0.758
5
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.755
6
UniProt:Q9P2B4 CT2NL
0.737
5
UniProt:P30153 PPP2R1A
2
PPP2R1A [cytosol]
(R-HSA-165982)
PPP2R1A [nucleoplasm]
(R-HSA-165968)
0.725
4
UniProt:Q14BN4 SLMAP
0.725
4
UniProt:Q8WZ74 CTTB2
0.69
4
UniProt:Q9NRL3 STRN4
0.643
3
UniProt:O00506 STK25
0.643
4
UniProt:Q9Y6E0 STK24
4
STK24(1-313) [nucleoplasm]
(R-HSA-351944)
STK24(314-443) [cytosol]
(R-HSA-351898)
STK24(1-313) [cytosol]
(R-HSA-351892)
STK24 [cytosol]
(R-HSA-351829)
0.643
4
UniProt:Q5VSL9 STRP1
0.623
3
UniProt:Q9P289 STK26
3
MST4(306-416) [cytosol]
(R-HSA-351903)
MST4(1-305) [cytosol]
(R-HSA-351855)
MST4 [cytosol]
(R-HSA-351918)
0.593
4
UniProt:Q9Y376 CAB39
4
CAB39 [secretory granule lumen]
(R-HSA-6801288)
CAB39 [extracellular region]
(R-HSA-6806462)
CAB39 [ficolin-1-rich granule lumen]
(R-HSA-6801287)
CAB39 [cytosol]
(R-HSA-380969)
0.544
6
UniProt:P67775 PPP2CA
4
MeL-PPP2CA [nucleoplasm]
(R-HSA-8857791)
PPP2CA [cytosol]
(R-HSA-165971)
PPP2CA [nucleoplasm]
(R-HSA-165978)
p-Y307-PPP2CA [cytosol]
(R-HSA-8857939)
0.527
2
UniProt:Q9BRV8 SIKE1
1
SIKE1 [cytosol]
(R-HSA-916828)
0.527
2
UniProt:Q7L7X3 TAOK1
1
TAOK1 [cytosol]
(R-HSA-376248)
0.527
2
UniProt:Q9ULQ0 STRP2
0.527
2
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