Reactome | SLC38A1 (ATA1)-mediated uptake of neutral amino acids

SLC38A1 (ATA1)-mediated uptake of neutral amino acids

Stable Identifier

R-HSA-352119

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

SLC38A1 (ATA1)-mediated uptake of neutral amino acids

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

SLC38A1 (ATA1), associated with the plasma membrane, mediates the uptake of neutral amino acids, especially alanine, asparagine, glutamine, methionine, and serine in a sodium ion-dependent transport process. Northern blotting experiments indicate gene expression in placenta and heart, and at lower levels in other tissues including brain, lung, skeletal muscle, spleen, stomach and testis, but not kidney or intestine (Wang et al. 2000).

Literature References

PubMed ID	Title	Journal	Year
10891391	Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta Sugawara, M, Leibach, FH, Ganapathy, V, Huang, W, Devoe, LD, Prasad, PD, Wang, H	Biochem Biophys Res Commun	2000