SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine

Stable Identifier
R-HSA-352364
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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SLC1A4, associated with the plasma membrane, mediates the exchange of alanine and an extracellular sodium ion for a cytosolic sodium ion and any one of the four amino acids alanine, serine, threonine, or cysteine (Zerangue and Kavanaugh 1996).

Literature References
PubMed ID Title Journal Year
8910405 ASCT-1 is a neutral amino acid exchanger with chloride channel activity

Zerangue, N, Kavanaugh, MP

J Biol Chem 1996
8101838 Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family

Arriza, JL, Kavanaugh, MP, Fairman, WA, Wu, YN, Murdoch, GH, North, RA, Amara, SG

J Biol Chem 1993
8340364 Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters

Shafqat, S, Tamarappoo, BK, Kilberg, MS, Puranam, RS, McNamara, JO, GuadaƱo-Ferraz, A, Fremeau RT, Jr

J Biol Chem 1993
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
amino acid transmembrane transporter activity of SLC1A4 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created