SRC-1 [cytosol]

Stable Identifier
R-HSA-354153
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Proto-oncogene tyrosine-protein kinase SRC (EC 2.7.1.112) (p60-SRC) (C-SRC), Proto-oncogene tyrosine-protein kinase Src , p60-Src, c-Src, SRC1, SRC isoform 1
Icon
SRC-1 [cytosol] icon
SRC-1 [cytosol] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P12931-1 SRC
Gene Names
SRC, SRC1
Participates
as a component of
as an input of
as a member of
Other forms of this molecule
Activated SRC-1 [cytosol]
p-Y419-SRC-1 [plasma membrane]
p-Y419-SRC [cytosol]
SRC-1 [plasma membrane]
Inferred To
Ghost homologue of SRC-1 [cytosol] (Xenopus tropicalis)
SRC_RAT [cytosol] (Rattus norvegicus)
SRC [cytosol] (Canis familiaris)
SRC-2 [cytosol] (Bos taurus)
SRC-2 [cytosol] (Caenorhabditis elegans)
SRC-2 [cytosol] (Danio rerio)
SRC-2 [cytosol] (Drosophila melanogaster)
SRC-2 [cytosol] (Gallus gallus)
SRC-2 [cytosol] (Mus musculus)
SRC-2 [cytosol] (Sus scrofa)
Interactors (76)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P18031 PTPN1  2 0.937 14
 UniProt:Q05397 PTK2  11 0.924 9
 UniProt:P00533 EGFR  20 0.9 9
 UniProt:P03372 ESR1  10 0.848 12
 UniProt:P22681 CBL  20 0.845 8
 UniProt:Q9H5V8 CDCP1      0.793 5
 UniProt:P08581 MET  7 0.787 7
 UniProt:P27986 PIK3R1  16 0.779 7
 UniProt:P35968 KDR  5 0.77 6
 UniProt:Q13444 ADAM15  1 0.75 4
 UniProt:P15941 MUC1  19 0.748 5
 UniProt:P18433 PTPRA  1 0.734 5
 UniProt:Q16543 CDC37  1 0.708 6
 UniProt:P04626 ERBB2  20 0.708 11
 UniProt:P56945 BCAR1  4 0.688 3
 UniProt:Q01973 ROR1  2 0.682 9
 UniProt:P07948 LYN  7 0.669 4
 UniProt:P07900 HSP90AA1  8 0.669 3
 UniProt:P06241 FYN  6 0.669 5
 UniProt:Q9H204 MED28  1 0.656 3
 UniProt:Q8WUM4 PDCD6IP  1 0.653 7
 UniProt:P55196 AFDN      0.65 7
 UniProt:Q14289 PTK2B  3 0.643 3
 UniProt:P49407 ARRB1  6 0.623 3
 UniProt:Q92569 PIK3R3  2 0.621 3
 UniProt:P07550 ADRB2  5 0.611 3
 UniProt:Q9ULH1 ASAP1  1 0.609 3
 UniProt:P35326 SPRR2A  2 0.602 3
 UniProt:Q62884 Q62884      0.602 3
 UniProt:P61978 HNRNPK  2 0.593 6
 UniProt:Q68CZ2 TNS3  1 0.591 13
 UniProt:P27635 RPL10  1 0.591 6
 UniProt:P16284 PECAM1  5 0.59 3
 UniProt:P00519 ABL1  6 0.589 2
 UniProt:Q07666 KHDRBS1  3 0.573 3
 UniProt:P01112 HRAS  20 0.571 2
 UniProt:P34152 Ptk2  13 0.564 2
 UniProt:P68400 CSNK2A1  2 0.564 2
 UniProt:P32121 ARRB2  3 0.564 2
 ChEBI:15532 MYRISTOYL-COA      0.558 2
 UniProt:O43184 ADAM12  1 0.558 2
 UniProt:Q8R5G7  1 0.558 3
 linoleoyl-CoA [ChEBI:15530]  2 0.558 2
 UniProt:Q9BR61 ACBD6  1 0.558 4
 UniProt:P27986-2 PIK3R1      0.556 3
 UniProt:Q13829 TNFAIP1  1 0.556 3
 UniProt:Q9UNY5 ZN232      0.556 3
 UniProt:O14796 SH2D1B  1 0.556 3
 UniProt:Q13322-4 GRB10      0.556 3
 UniProt:Q6XD76 ASCL4      0.556 3
 UniProt:Q8TBB1 LNX1  1 0.556 6
 UniProt:Q15907 RAB11B  3 0.556 3
 UniProt:O60880 SH2D1A  1 0.556 3
 UniProt:Q14457 BECN1  4 0.556 3
 UniProt:Q14693 LPIN1  3 0.556 3
 UniProt:Q9UIH9 KLF15  1 0.556 3
 UniProt:Q9BU70 TRMO      0.547 2
 UniProt:P97288  1 0.544 2
 UniProt:P25962  1 0.544 2
 UniProt:O14672 ADAM10  6 0.544 3
 UniProt:P35222 CTNNB1  20 0.544 2
 UniProt:P05023 ATP1A1  1 0.527 5
 UniProt:P40763 STAT3  12 0.527 5
 UniProt:P49023 PXN  4 0.527 2
 UniProt:P08238 HSP90AB1  6 0.527 2
 UniProt:P12814 ACTN1  3 0.524 2
 UniProt:P19367 HK1  4 0.524 2
 UniProt:Q13177 PAK2  11 0.524 2
 UniProt:P12830 CDH1  8 0.499 2
 UniProt:Q9H3S7 PTPN23  1 0.499 2
 UniProt:Q9Y6K9 IKBKG  12 0.499 3
 ChEBI:39112 BOSUTINIB      0.499 2
 ChEBI:45783 IMATINIB      0.499 2
 UniProt:P13569 CFTR  17 0.483 4
 UniProt:O15455 TLR3  6 0.463 2
 UniProt:P23743 DGKA  1 0.462 2
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