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ARHGEF15 [cytosol]
Stable Identifier
R-HSA-3550803
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rho guanine nucleotide exchange factor 15, Ephexin5
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ARHGEF15 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ARHGEF15 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
ARHGEF15 [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
ARHGEF15 [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
ARHGEF15 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O94989 ARHGEF15
Gene Names
ARHGEF15, KIAA0915
Chain
chain:1-841
Reference Genes
BioGPS Gene:22899 ARHGEF15
COSMIC (genes):ARHGEF15 ARHGEF15
CTD Gene:22899 ARHGEF15
dbSNP Gene:22899 ARHGEF15
ENSEMBL:ENSG00000198844 ARHGEF15
HGNC:15590 ARHGEF15
KEGG:hsa:22899 ARHGEF15
Monarch:22899 ARHGEF15
NCBI Gene:22899 ARHGEF15
OMIM:608504 ARHGEF15
UCSC:O94989 ARHGEF15
Reference Transcript
RefSeq:NM_025014.1 ARHGEF15
RefSeq:NM_173728.3 ARHGEF15
Other Identifiers
11722876_at
11750721_a_at
16830957
205507_PM_at
205507_at
217348_3p_x_at
217348_PM_x_at
217348_x_at
22899
3709605
3709606
3709607
3709608
3709609
3709610
3709611
3709612
3709613
3709614
3709615
3709616
3709617
3709618
3709619
3709620
3709622
3709623
3709624
3709626
3709627
3709628
3709629
3709630
3709631
3709632
3709633
3709634
3709635
38235_at
66362_at
8004842
A_14_P103051
A_23_P49674
A_24_P359007
GE53581
GO:0005085
GO:0005096
GO:0005515
GO:0005737
GO:0005829
GO:0030425
GO:0042995
GO:0050790
GO:0051056
GO:0051496
GO:0061299
GO:0098772
GO:0098794
GO:0098978
GO:0150052
GO:2000297
HMNXSV003056541
Hs.16714.1.S1_3p_at
Hs.16714.1.S1_3p_x_at
ILMN_1792571
PH_hs_0025879
TC17000138.hg
g7662377_3p_at
Participates
as a member of
RHOA GEFs [cytosol] (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
as a candidate of
RAC1 GEFs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
Inferred To
Exn [cytosol]
(Drosophila melanogaster)
ephx-1 [cytosol]
(Caenorhabditis elegans)
LOC116409847 [cytosol]
(Xenopus tropicalis)
Arhgef15 [cytosol]
(Mus musculus)
Arhgef15 [cytosol]
(Rattus norvegicus)
ARHGEF15 [cytosol]
(Bos taurus)
ARHGEF15 [cytosol]
(Canis familiaris)
ARHGEF15 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_776089.2
,
NP_079290.1
ENSEMBL
ENST00000361926
,
ENST00000421050
,
ENSP00000412505
,
ENSP00000355026
OpenTargets
ENSG00000198844
HPA
ENSG00000198844-ARHGEF15
PRO
O94989
Pharos - Targets
O94989
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13526 PIN1
2
PIN1 [nucleoplasm]
(R-HSA-936016)
PIN1 [cytosol]
(R-HSA-9626823)
0.556
3
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