Reactome | TGFBR1 LBD Mutants [plasma membrane]

TGFBR1 LBD Mutants [plasma membrane]

Stable Identifier

R-HSA-3656375

Type

Set [CandidateSet]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

TGFBR1 Ligand Binding Domain Mutants, TGFBR1 ECD Mutants, TGFBR1 Extracellular Domain Mutants

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
  - Signaling by TGF-beta Receptor Complex in Cancer (Homo sapiens)
    - Loss of Function of TGFBR1 in Cancer (Homo sapiens)
      - TGFBR1 LBD Mutants in Cancer (Homo sapiens)
        
        TGFBR2 does not recruit TGFBR1 LBD Mutants (Homo sapiens)
        
        TGFBR1 LBD Mutants:FKBP1A [plasma membrane] (Homo sapiens)
        
        TGFBR1 LBD Mutants [plasma membrane] (Homo sapiens)

Participants

members

TGFBR1 G52R [plasma membrane] (Homo sapiens)

candidates

Participates

as a component of

TGFBR1 LBD Mutants:FKBP1A [plasma membrane] (Homo sapiens)

Disease

Name	Identifier	Synonyms
cancer	DOID:162	malignant tumor, malignant neoplasm, primary cancer

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