Reactome | DR1 [nucleoplasm]

DR1 [nucleoplasm]

Stable Identifier

R-HSA-3662280

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein Dr1, NC2B_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q01658 DR1

Gene Names

DR1

Chain

initiator methionine:, chain:2-176

Reference Genes

BioGPS Gene:1810 DR1

COSMIC (genes):DR1 DR1

CTD Gene:1810 DR1

dbSNP Gene:1810 DR1

ENSEMBL:ENSG00000117505 DR1

ENSEMBL_homo_sapiens_GENE:ENSG00000117505.13 DR1

HGNC:3017 DR1

KEGG Gene (Homo sapiens):1810 DR1

Monarch:1810 DR1

NCBI Gene:1810 DR1

OMIM:601482 DR1

Reference Transcript

RefSeq:NM_001938.2 DR1

Other Identifiers

11722178_at

11722179_a_at

11722180_x_at

11752978_a_at

11753647_a_at

11758054_s_at

1558236_PM_at

1558236_at

1558237_PM_x_at

1558237_x_at

16667247

1810

207654_PM_x_at

207654_x_at

209187_PM_at

209187_at

209188_PM_x_at

209188_x_at

211_at

216652_PM_s_at

216652_s_at

2347097

2347098

2347099

2347100

2347101

2347102

2347104

2347107

2347108

2347109

2347110

2347111

2347112

2347113

2347114

2347115

2347116

2347117

2347118

235585_PM_at

235585_at

32621_at

52774_at

54465_at

58126_r_at

67562_at

7903079

82527_r_at

A_14_P202490

A_21_P0000189

A_23_P63205

GE472985

GE58179

GE877909

GO:0000122

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005856

GO:0006351

GO:0006355

GO:0006357

GO:0016251

GO:0017025

GO:0017054

GO:0036211

GO:0043226

GO:0045995

GO:0046982

GO:0048856

GO:0051123

GO:0051302

GO:0051726

GO:0065003

GO:0072686

GO:0090043

GO:0090575

GO:0140223

GO:0140672

HMNXSV003057038

Hs.16697.1.S2_3p_at

Hs.61406.0.A1_3p_at

Hs2.298058.1.S1_3p_at

Hs2.298058.1.S1_3p_x_at

ILMN_1759983

M97388_at

PH_hs_0003899

PH_hs_0015395

PH_hs_0023909

TC01000861.hg

g4503380_3p_s_at

Participates

as a component of

as an input of

Inferred To

zgc:152914 [nucleoplasm] (Danio rerio)

dr1 [nucleoplasm] (Dictyostelium discoideum)

dr1 [nucleoplasm] (Xenopus tropicalis)

DR1 [nucleoplasm] (Bos taurus)

DR1 [nucleoplasm] (Canis familiaris)

DR1 [nucleoplasm] (Gallus gallus)

DR1 [nucleoplasm] (Sus scrofa)

NC2beta [nucleoplasm] (Drosophila melanogaster)

NCB2 [nucleoplasm] (Saccharomyces cerevisiae)

dro-1 [nucleoplasm] (Caenorhabditis elegans)

Dr1 [nucleoplasm] (Mus musculus)

Dr1 [nucleoplasm] (Rattus norvegicus)

ncb2 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001929.1

OpenTargets

ENSG00000117505

GeneCards

Q01658

HPA

ENSG00000117505-DR1

Ensembl

ENSP00000359290, ENST00000370267, ENSP00000359295, ENSG00000117505, ENST00000370272

PRO

Q01658

Pharos - Targets

Q01658

PDB

1JFI

Interactors (75)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14919 DRAP1	1	DRAP1 [nucleoplasm] (R-HSA-1226029)	0.915	46
UniProt:Q9NRF9 POLE3	1	POLE3 [nucleoplasm] (R-HSA-8866685)	0.781	7
UniProt:P62701 RPS4X	2	RPS4X [nucleoplasm] (R-HSA-6798713) RPS4X [cytosol] (R-HSA-72375)	0.556	3
UniProt:Q96LL4 CH048			0.556	3
UniProt:Q96MN9-2 Q96MN92			0.556	3
UniProt:Q96IJ6 GMPPA	1	GMPPA [cytosol] (R-HSA-532565)	0.556	3
UniProt:Q5T6S3 PHF19	1	PHF19 [nucleoplasm] (R-HSA-5084115)	0.556	3
UniProt:Q92782-2 Q927822			0.556	3
UniProt:O15381-5 O153815			0.556	3
UniProt:A2RU56 A2RU56			0.556	3
UniProt:Q9P2T0 SPMA2			0.556	3
UniProt:Q9P0T4 ZN581			0.556	3
UniProt:O43615 TIMM44	1	TIMM44(?-452) [mitochondrial inner membrane] (R-HSA-1252038)	0.556	3
UniProt:P48730-2 CSNK1D			0.556	3
UniProt:Q969K3 RNF34	2	RNF34 [nucleoplasm] (R-HSA-6804442) RNF34 [cytosol] (R-HSA-975998)	0.556	3
UniProt:Q494V2-2 CFAP100			0.556	3
UniProt:Q6NXT2 H3C			0.556	3
UniProt:P01106 MYC	2	PolyUb-MYC [nucleoplasm] (R-HSA-6783169) MYC [nucleoplasm] (R-HSA-188379)	0.556	3
UniProt:Q13191 CBLB	1	CBLB [cytosol] (R-HSA-976009)	0.556	3
UniProt:Q9H000 MKRN2			0.556	3
UniProt:P40337-2 VHL			0.556	3
UniProt:Q8IZU1 FAM9A			0.556	3
UniProt:Q96D59 RN183			0.556	3
UniProt:Q9P2Y4 ZN219			0.556	3
UniProt:A0A384ME25 A0A384ME25			0.556	3
UniProt:Q8NBB4-2 ZSCAN1			0.556	3
UniProt:P13928 ANXA8			0.556	3
UniProt:Q9H972-2 C14ORF93			0.556	3
UniProt:Q9Y5P3 RAI2			0.556	3
UniProt:P46379-2 BAG6			0.556	3
UniProt:Q92615 LAR4B			0.556	3
UniProt:Q15049 MLC1			0.556	3
UniProt:Q8TCT7-2 SPPL2B			0.556	3
UniProt:Q92613 JADE3	1	PHF16 [nucleoplasm] (R-HSA-3321851)	0.556	3
UniProt:Q6P1L5 F117B			0.556	3
UniProt:Q32MN6 Q32MN6			0.556	3
UniProt:Q17RN3 FA98C			0.556	3
UniProt:Q8NHS9 SPT22			0.556	3
UniProt:Q14693 LPIN1	3	p-S106-LPIN1 [nucleoplasm] (R-HSA-4419936) LPIN1 [nuclear envelope] (R-HSA-4419927) LPIN1 [endoplasmic reticulum membrane] (R-HSA-549157)	0.556	3
UniProt:Q5TAQ9-2 Q5TAQ92			0.556	3
UniProt:P58304 VSX2			0.556	3
UniProt:Q99873-2 PRMT1			0.556	3
UniProt:O95563 MPC2	1	MPC2 [mitochondrial inner membrane] (R-HSA-2512891)	0.556	3
IntAct:EBI-25835796 CCSB			0.556	3
UniProt:Q04603	1	DPB4 [nucleoplasm] (R-SCE-8866685)	0.556	3
UniProt:Q9H7T9 AUNIP			0.556	3
UniProt:Q9HCC6 HES4			0.556	3
UniProt:Q9BYU1 PBX4			0.556	3
UniProt:Q8TD91-2 MAGEC3			0.556	3
UniProt:Q8TBE0 BAHD1			0.556	3
IntAct:EBI-25835277 CCSB			0.556	3
UniProt:Q9BVN2 RUSC1			0.556	3
UniProt:Q53FD0-2 ZC2HC1C			0.556	3
IntAct:EBI-25831191 CCSB			0.556	3
UniProt:Q9HBQ8 GGA2B			0.556	3
UniProt:Q9UIH9 KLF15	1	KLF15 [nucleoplasm] (R-HSA-8878735)	0.556	3
UniProt:P60896 SEM1	2	SEM1 [nucleoplasm] (R-HSA-8866665) SEM1 [cytosol] (R-HSA-8866674)	0.556	3
UniProt:P19388 POLR2E	2	POLR2E [nucleoplasm] (R-HSA-83713) POLR2E [cytosol] (R-HSA-1964438)	0.556	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:Q8N488 RYBP	1	RYBP [nucleoplasm] (R-HSA-8937975)	0.556	3
UniProt:Q13123 IK	1	IK [nucleoplasm] (R-HSA-9770239)	0.556	3
UniProt:O75604-3 USP2			0.556	3
UniProt:Q9Y4H4 GPSM3	1	GPSM3 [cytosol] (R-HSA-8949486)	0.556	3
UniProt:Q9NRL3 STRN4			0.556	3
UniProt:Q13952-2 NFYC			0.556	3
UniProt:O75446 SAP30	1	SAP30 [nucleoplasm] (R-HSA-351693)	0.556	3
UniProt:Q9H669 Q9H669			0.556	3
UniProt:Q86TI2-2 Q86TI22			0.556	3
UniProt:Q3KNS6-3 Q3KNS63			0.556	3
UniProt:P10073 ZSC22			0.556	3
UniProt:Q6XD76 ASCL4			0.556	3
UniProt:Q9Y6C2-2 EMILIN1			0.556	3
UniProt:Q9BSH4 TACO1	1	TACO1 [mitochondrial matrix] (R-HSA-5336153)	0.556	3
UniProt:O60506-4 SYNCRIP			0.556	3
UniProt:Q9BUL9 RPP25	1	RPP25 [nucleoplasm] (R-HSA-5696782)	0.556	3

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