TP53 stimulates MDM2 transcription

Stable Identifier
R-HSA-3700992
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Binding of TP53 (p53) to the p53 response element in the first intron of the MDM2 gene stimulates MDM2 transcription (Wu et al. 1993).

Literature References
PubMed ID Title Journal Year
8319905 The p53-mdm-2 autoregulatory feedback loop Genes Dev. 1993
Participants
Participant Of
This entity is regulated by