Reactome | SLC25A1 [mitochondrial inner membrane]

SLC25A1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-372445

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

tricarboxylate (citrate) transporter

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P53007 SLC25A1

Gene Names

SLC25A1, SLC20A3

Chain

propeptide:1-13, chain:14-311

Reference Genes

BioGPS Gene:6576 SLC25A1

COSMIC (genes):SLC25A1 SLC25A1

CTD Gene:6576 SLC25A1

dbSNP Gene:6576 SLC25A1

ENSEMBL:ENSG00000100075 SLC25A1

HGNC:10979 SLC25A1

KEGG:hsa:6576 SLC25A1

Monarch:6576 SLC25A1

NCBI Gene:6576 SLC25A1

OMIM:190315 SLC25A1

UCSC:P53007 SLC25A1

Reference Transcript

RefSeq:NM_005984.4 SLC25A1

Other Identifiers

11756675_x_at

16932204

210010_PM_s_at

210010_s_at

38998_g_at

3952544

3952545

3952546

3952547

3952548

3952549

3952550

3952552

3952553

3952554

3952555

3952556

3952557

3952558

3952559

3952560

3952561

3952562

3952563

3952564

39825_at

6576

8074388

GE57798

GO:0005215

GO:0005634

GO:0005739

GO:0005743

GO:0006811

GO:0006843

GO:0015137

GO:0015142

GO:0015297

GO:0016020

GO:0043226

GO:0055085

GO:0070062

GO:0071913

HMNXSV003024452

ILMN_1813671

L77567_s_at

PH_hs_0031529

TC22000494.hg

TC22001214.hg

g950003_3p_s_at

Participates

as a candidate of

SLC25A1 [mitochondrial inner membrane] (Homo sapiens)

Inferred To

CTP1 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

sea [mitochondrial inner membrane] (Drosophila melanogaster)

slc25a1b [mitochondrial inner membrane] (Danio rerio)

Slc25a1 [mitochondrial inner membrane] (Mus musculus)

Slc25a1 [mitochondrial inner membrane] (Rattus norvegicus)

SLC25A1 [mitochondrial inner membrane] (Bos taurus)

SLC25A1 [mitochondrial inner membrane] (Caenorhabditis elegans)

SLC25A1 [mitochondrial inner membrane] (Canis familiaris)

SLC25A1 [mitochondrial inner membrane] (Gallus gallus)

SLC25A1 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

SLC25A1 [mitochondrial inner membrane] (Sus scrofa)

slc25a1 [mitochondrial inner membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_005975.1

Guide to Pharmacology - Targets

1051

ENSEMBL

ENST00000215882, ENSP00000215882

OpenTargets

ENSG00000100075

HPA

ENSG00000100075-SLC25A1

PRO

P53007

Pharos - Targets

P53007

GlyGen

P53007

Orphanet

SLC25A1

HMDB Protein

HMDBP01599

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	8

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