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ELMO1,ELMO2 [cytosol]
Stable Identifier
R-HSA-372640
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
CRKII:DOCK180:ELMO binds FCGR3A (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:CRKII:DOCK180:ELMO [plasma membrane] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
DOCK180 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:CRKII:DOCK180:ELMO [plasma membrane] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Activation of RAC1 by CRKII:DOCK180:ELMO (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Non-Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PTK6 (Homo sapiens)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Homo sapiens)
Activation of RAC1 by the PXN:CRK complex (Homo sapiens)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
Phosphorylated PXN recruits the CRK complex (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
DOCK180:ELMO binds CRK (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
ELMO1,ELMO2 [cytosol] (Homo sapiens)
Participants
members
ELMO1 [cytosol]
(Homo sapiens)
ELMO2 [cytosol]
(Homo sapiens)
Participates
as a component of
DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Homo sapiens)
Inferred To
ELMO1,ELMO2 [cytosol]
(Bos taurus)
ELMO1,ELMO2 [cytosol]
(Canis familiaris)
ELMO1,ELMO2 [cytosol]
(Dictyostelium discoideum)
ELMO1,ELMO2 [cytosol]
(Gallus gallus)
ELMO1,ELMO2 [cytosol]
(Mus musculus)
ELMO1,ELMO2 [cytosol]
(Rattus norvegicus)
ELMO1,ELMO2 [cytosol]
(Sus scrofa)
ELMO1,ELMO2 [cytosol]
(Xenopus tropicalis)
Ced-12 [cytosol]
(Drosophila melanogaster)
LMO1 [cytosol]
(Saccharomyces cerevisiae)
ced-12 [cytosol]
(Caenorhabditis elegans)
Ghost homologue of ELMO1,ELMO2 [cytosol]
(Danio rerio)
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