Reactome: A Curated Pathway Database

malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]

Stable Identifier
R-HSA-372843
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

SLC25A10, the mitochondrial dicarboxylate carrier protein in the inner mitochondrial membrane, mediates the reversible exchange of mitochondrial malate for cytosolic phosphate (Fiermonte et al. 1999).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
dicarboxylic acid transmembrane transporter activity of SLC25A10 [mitochondrial inner membrane] SLC25A10 [mitochondrial inner membrane] dicarboxylic acid transmembrane transporter activity (0005310)
Orthologous Events