Reactome | CNTN2 [plasma membrane]

CNTN2 [plasma membrane]

Stable Identifier

R-HSA-373618

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Axonin-1, Contactin-2, CNTN2_HUMAN, TAG1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q02246 CNTN2

Gene Names

CNTN2, AXT, TAG1, TAX1

Chain

signal peptide:1-30, chain:31-1012, propeptide:1013-1040

Reference Genes

BioGPS Gene:6900 CNTN2

COSMIC (genes):CNTN2 CNTN2

CTD Gene:6900 CNTN2

dbSNP Gene:6900 CNTN2

ENSEMBL:ENSG00000184144 CNTN2

ENSEMBL_homo_sapiens_GENE:ENSG00000184144.12 CNTN2

HGNC:2172 CNTN2

KEGG Gene (Homo sapiens):6900 CNTN2

Monarch:6900 CNTN2

NCBI Gene:6900 CNTN2

OMIM:190197 CNTN2

UCSC:Q02246 CNTN2

Reference Transcript

Other Identifiers

11726789_a_at

11726790_a_at

11726791_at

16676405

206970_PM_at

206970_at

230045_PM_at

230045_at

2376300

2376301

2376303

2376304

2376305

2376306

2376307

2376309

2376310

2376311

2376312

2376313

2376314

2376315

2376316

2376318

2376319

2376320

2376321

2376322

2376323

2376326

2376328

2376329

2376330

2376331

2376332

2376333

2376334

2376335

2376336

2376337

2376338

2376339

2376341

2376342

36276_at

52440_at

6900

7909064

A_23_P63557

A_24_P114142

A_24_P2901

GE59940

GO:0002021

GO:0002023

GO:0005515

GO:0005886

GO:0007155

GO:0007156

GO:0007411

GO:0016020

GO:0030154

GO:0030424

GO:0033268

GO:0034330

GO:0043194

GO:0043209

GO:0044224

GO:0045163

GO:0045202

GO:0045211

GO:0045444

GO:0048856

GO:0061024

GO:0070593

GO:0071205

GO:0071206

GO:0097090

GO:0098552

GO:0098631

GO:0098632

HMNXSV003007746

Hs.31599.0.A1_3p_at

ILMN_1718896

PH_hs_0000377

TC01001705.hg

X67734_at

g4827021_3p_at

Participates

as a component of

as an input of

Cross References

RefSeq

NP_005067.1, NP_001333012.1

OpenTargets

ENSG00000184144

HPA

ENSG00000184144-CNTN2

GeneCards

Q02246

Ensembl

ENSP00000330633, ENSP00000491671, ENSG00000184144, ENST00000639302, ENSP00000492495, ENST00000638378, ENST00000331830, ENST00000640326, ENSP00000492617

PRO

Q02246

Pharos - Targets

Q02246

Orphanet

22039

PDB

2OM5

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2

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