Nephrin binds CASK

Stable Identifier
R-HSA-373722
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

CASK is a scaffolding protein that participates in maintenance of polarized epithelial cell architecture by linking membrane proteins and signaling molecules to the actin cytoskeleton. CASK is identified as one of the binding partners of nephrin and this interaction likely plays an important role in establishing the structural integrity and functional properties of the glomerular slit diaphragm.

Participants
Participant Of
Inferred From