Neurofascin binds Ankyrin-G

Stable Identifier
R-HSA-373729
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The cytoplasmic domains of neurofascin contains a highly conserved sequence (F1315IGQY) that binds ankyrin. The membrane binding domain of ankyrin has two distinct binding sites for neurofascin and is proposed to form lateral complexes between ion channels and cell adhesion molecules as well as to couple these proteins to the spectrin based membrane skeleton.

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