Reactome: A Curated Pathway Database

BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol

Stable Identifier
R-HSA-373867
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
lactate + H+ [extracellular] <=> lactate + H+ [cytosol]
Locations in the PathwayBrowser
Summation

The membrane-associated MCT:basigin complex mediates the reversible uptake of extracellular lactate and H+ (Wilson et al. 2005).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
lactate transmembrane transporter activity of BSG:MCTs [plasma membrane] BSG:MCTs [plasma membrane] lactate transmembrane transporter activity (0015129)
Orthologous Events