DCC interaction with SIAH1

Stable Identifier
R-HSA-374665
Type
Reaction
Species
Homo sapiens
Compartment
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General
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Siah-1 binds DCC and promotes its proteolysis via the ubiquitin-proteasome pathway. Siah-1 contains an N-terminal RING domain that is involved in proteolysis function and a C-terminal sequence that is involved in its oligomerization and binding to target proteins, such as DCC.

Participants
Participant Of
Event Information
Orthologous Events
Authored
Reviewed
Created