Reactome: A Curated Pathway Database

L1 binds RanBPM

Stable Identifier
R-HSA-374673
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

L1 and RanBPM interact with one another and the N-terminus of RanBPM was sufficient for the interaction with L1. RanBPM interacts with RAN, a Ras-like small GTPase that functions as a carrier in nuclear-cytoplasmic exchange. It directly interacts with Sos to activate Ras and induce ERK phosphorylation. RanBPM might function as an adaptor to mediate L1-induced ERK activation.

Literature References
Participants
Participant Of
Orthologous Events