Reactome | EPCAM [plasma membrane]

EPCAM

Stable Identifier

R-HSA-375068

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Tumor-associated calcium signal transducer 1, TACD1_HUMAN, TACSTD1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P16422 EPCAM

Gene Names

EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1

Chain

signal peptide:1-23, chain:24-314

Reference Genes

KEGG Gene (Homo sapiens):4072 EPCAM, dbSNP Gene:4072 EPCAM, Monarch:4072 EPCAM, OMIM:613217 EPCAM, OMIM:613244 EPCAM, OMIM:185535 EPCAM, HGNC:11529 EPCAM, ENSEMBL:ENSG00000119888 EPCAM, COSMIC (genes):EPCAM EPCAM, BioGPS Gene:4072 EPCAM, CTD Gene:4072 EPCAM, NCBI Gene:4072 EPCAM

Reference Transcript

RefSeq:NM_002354.2 EPCAM

Other Identifiers

11716887_a_at	11745651_a_at	11745652_s_at	16879863	201839_s_at
2480966	2480967	2480968	2480972	2480973
2480974	2480975	2480976	2480977	2480978
2480980	2480981	2480982	2480984	2480987
2480988	2480989	26761	2753287	2753288
2753289	30012	3809	4072	4MZV
55098	575_s_at	67463	8041853	8098439
A_14_P113932	A_23_P91081	AAA35723	AAA35861	AAA36151
AAA59543	AAB00775	AAH14785	AAY15095	AC079775
BC014785	CAA32870	CAB003809	CAB030012	CAB055098
CAG47055	CAG47078	CCDS1833	CH471053	CR542259
CR542283	EAX00218	ENSG00000119888	ENSP00000263735	ENST00000263735
EntrezGene:4072	EPCAM	EPCAM-201	g4505058_3p_a_at	GE60518
GO:0001657	GO:0002376	GO:0003674	GO:0005515	GO:0005575
GO:0005576	GO:0005623	GO:0005886	GO:0005887	GO:0005923
GO:0007155	GO:0007165	GO:0008150	GO:0008219	GO:0008283
GO:0008284	GO:0009058	GO:0009986	GO:0016020	GO:0016021
GO:0016323	GO:0016324	GO:0016328	GO:0023019	GO:0030054
GO:0030154	GO:0032403	GO:0034641	GO:0040011	GO:0043066
GO:0043226	GO:0045944	GO:0048856	GO:0048863	GO:0048870
GO:0050900	GO:0070062	GO:0098641	GO:0098742	GO:2000048
GO:2000147	GO:2000648	HGNC:11529	HPA026761	HPA067463
Hs.542050	ILMN_1673871	ILMN_2160210	ILMN_3249032	IPR000716
LRG_215	LRG_215t1	M26481	M32306	M32325
M33011	M93029	M93030	M93031	M93032
M93033	M93034	M93035	M93036	M93036_at
MIM:185535	MIM:613217	MIM:613244	NM_002354	NP_002345
PF00086	PH_hs_0000078	SM00211	TC02000293.hg	uc002rvx.4
UPI000013D450	X14758

Participant Of

input

EPCAM binds itself to form homotypic cell adhesion

hasComponent

EPCAM dimer [plasma membrane]

Inferred To

Cross References

RefSeq

NP_002345.2

UCSC human

P16422

GeneCards

P16422

DOCK Blaster

4MZV

PRO

P16422

Orphanet

19023

PDB

4MZV

Interactors

Confidence Score	Interactor Accession	Interactor Name	Evidence (IntAct)

0.462

CHEBI:16618

1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,4,5-TRISPHOSPHATE