Hormone ligand-binding receptors

Stable Identifier
R-HSA-375281
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser

The class A (rhodopsin-like) GPCRs that bind to hormone ligands are annotated here. The hormones follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH) and human chorionic gonadotrophin (hCG) are dimeric glycoproteins, sharing an identical alpha subunit and varying beta subunits. Their actions are mediated by the respective GPCRs, influencing reproductive processes and thyroid hormone release.

Literature References
PubMed ID Title Journal Year
11750726 Structural biology of human follitropin and its receptor

Dias, JA, Van Roey, P

Arch Med Res 2001
11917095 Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships

Szkudlinski, MW, Fremont, V, Ronin, C, Weintraub, BD

Physiol Rev 2002
11861490 GnRH and GnRH receptor genes in the human genome

Neill, JD

Endocrinology 2002
11943741 The lutropin/choriogonadotropin receptor, a 2002 perspective

Ascoli, M, Fanelli, F, Segaloff, DL

Endocr Rev 2002
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created