Reactome | SLC36A1 [plasma membrane]

SLC36A1 [plasma membrane]

Stable Identifier

R-HSA-375419

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

PAT1, Proton-coupled amino acid transporter 1

Locations in the PathwayBrowser for interactor UniProt:P05067

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External Reference Information

External Reference

UniProt:Q7Z2H8 SLC36A1

Gene Names

SLC36A1, PAT1

Chain

chain:1-476

Reference Genes

BioGPS Gene:206358 SLC36A1

COSMIC (genes):SLC36A1 SLC36A1

CTD Gene:206358 SLC36A1

dbSNP Gene:206358 SLC36A1

ENSEMBL:ENSG00000123643 SLC36A1

ENSEMBL_homo_sapiens_GENE:ENSG00000123643.14 SLC36A1

HGNC:18761 SLC36A1

KEGG Gene (Homo sapiens):206358 SLC36A1

Monarch:206358 SLC36A1

NCBI Gene:206358 SLC36A1

OMIM:606561 SLC36A1

UCSC:Q7Z2H8 SLC36A1

Reference Transcript

Other Identifiers

11721979_at

11721980_a_at

11721981_x_at

11745410_a_at

11752945_a_at

11758175_s_at

1553272_PM_at

1553272_at

206358

213119_PM_at

213119_at

2835849

2835850

2835851

2835852

2835865

2835866

2835867

2835868

2835871

2835872

2835874

2835877

2835878

2835880

2835881

2835885

2835886

2835887

2835888

2835890

2881956

40923_at

66058_r_at

80203_at

80205_at

8109350

A_23_P167640

A_33_P3251093

GE55605

GO:0005215

GO:0005280

GO:0005297

GO:0005368

GO:0005515

GO:0005764

GO:0005765

GO:0005773

GO:0005774

GO:0005783

GO:0005886

GO:0006811

GO:0006865

GO:0015171

GO:0015180

GO:0015187

GO:0015193

GO:0015293

GO:0015734

GO:0015808

GO:0015816

GO:0015824

GO:0016020

GO:0016324

GO:0022858

GO:0032328

GO:0035524

GO:0043226

GO:0055085

GO:0089718

GO:1902600

HMNXSV003004301

HMNXSV003011218

Hs.18593.0.A1_3p_at

Hs2.146612.1.S1_3p_at

Hs2.146612.1.S1_3p_x_at

ILMN_2124471

PH_hs_0024794

Inferred To

AVT4 [plasma membrane] (Saccharomyces cerevisiae)

SLC36A1 [plasma membrane] (Bos taurus)

SLC36A1 [plasma membrane] (Canis familiaris)

SLC36A1 [plasma membrane] (Dictyostelium discoideum)

SLC36A1 [plasma membrane] (Gallus gallus)

SLC36A1 [plasma membrane] (Sus scrofa)

Slc36a1 [plasma membrane] (Mus musculus)

Slc36a1 [plasma membrane] (Rattus norvegicus)

Dmel\CG13384 [plasma membrane] (Drosophila melanogaster)

slc-36.1 [plasma membrane] (Caenorhabditis elegans)

slc36a1 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_016864705.1, XP_011535890.1, XP_011535888.1, XP_011535889.1, XP_011535891.1, XP_016864709.1, XP_011535883.1, NP_510968.2, XP_005268443.1, XP_011535893.1, XP_011535887.1, XP_011535894.1, XP_011535885.1, NP_001295079.1, NP_001295080.1, XP_011535886.1, XP_011535892.1

Guide to Pharmacology - Targets

1161

OpenTargets

ENSG00000123643

HPA

ENSG00000123643-SLC36A1

GeneCards

Q7Z2H8

ZINC target

Q7Z2H8

Ensembl

ENSP00000243389, ENSP00000395640, ENST00000243389, ENST00000520701, ENST00000429484, ENSG00000123643, ENSP00000428140

PRO

Q7Z2H8

Pharos - Targets

Q7Z2H8

HMDB Protein

HMDBP03592

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:A5PKU2 A5PKU2			0.556	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3

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