Reactome | WIF1 [extracellular region]

WIF1 [extracellular region]

Stable Identifier

R-HSA-3769320

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y5W5 WIF1

Gene Names

WIF1, UNQ191/PRO217

Chain

signal peptide:1-28, chain:29-379

Reference Genes

BioGPS Gene:11197 WIF1

COSMIC (genes):WIF1 WIF1

CTD Gene:11197 WIF1

dbSNP Gene:11197 WIF1

ENSEMBL:ENSG00000156076.10 WIF1

HGNC:18081 WIF1

KEGG Gene (Homo sapiens):11197 WIF1

Monarch:11197 WIF1

NCBI Gene:11197 WIF1

OMIM:605186 WIF1

UCSC:Q9Y5W5 WIF1

Reference Transcript

RefSeq:NM_007191.4 WIF1

Other Identifiers

0002940750

11197

11742807_a_at

16767081

204712_PM_at

204712_at

3460215

3460216

3460218

3460219

3460222

3460225

3460226

3460229

3460230

3460231

3460241

3460242

3460243

35178_at

7964722

A_32_P216520

A_32_P9941

GE58440

GO:0005102

GO:0005515

GO:0005576

GO:0007165

GO:0009986

GO:0016055

GO:0017147

GO:0023052

GO:0030154

GO:0030178

GO:0045600

GO:0048856

HMNXSV003023958

ILMN_1721541

ILMN_1790050

PH_hs_0014708

TC12001681.hg

g6005949_3p_at

Participates

as an input of

WIF1 binds WNTs (Homo sapiens)

as a component of

WIF1:WNT [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_009122.2

OpenTargets

ENSG00000156076

GeneCards

Q9Y5W5

HPA

ENSG00000156076-WIF1

Ensembl

ENSP00000286574, ENSG00000156076, ENST00000286574

PRO

Q9Y5W5

Pharos - Targets

Q9Y5W5

PDB

2YGP, 2YGQ, 2D3J, 2YGO, 2YGN

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.718	6
UniProt:P27467 Wnt3a	12	Wnt3a [extracellular exosome] (R-MMU-3781968) Wnt3a [endocytic vesicle membrane] (R-MMU-3781944) N4GlycoAsn-PalmS Wnt3a [extracellular region] (R-MMU-3769340) Wnt3a [extracellular region] (R-MMU-3772390) Wnt3a [early endosome membrane] (R-MMU-5368483) N4GlycoAsn-PalmS Wnt3a [endoplasmic reticulum lumen] (R-MMU-3238346) N-glycosyl Wnt3a [endoplasmic reticulum lumen] (R-MMU-3238233) Wnt3a [endoplasmic reticulum lumen] (R-MMU-3238294) Wnt3a [endoplasmic reticulum lumen] (R-MMU-3238344) Wnt3a [Golgi lumen] (R-MMU-3247832) Wnt3a [extracellular region] (R-MMU-3247784) Wnt3a [plasma membrane] (R-MMU-3247807)	0.676	8
UniProt:O00755 WNT7A	9	WNT7A [extracellular region] (R-HSA-517404) N4GlycoAsn-PalmS WNT7A [extracellular exosome] (R-HSA-3781951) N4GlycoAsn-PalmS WNT7A [endocytic vesicle membrane] (R-HSA-3781961) WNT7A [endoplasmic reticulum lumen] (R-HSA-3238312) N4GlycoAsn-WNT7A [endoplasmic reticulum lumen] (R-HSA-3238249) N4GlycoAsn-PalmS WNT7A [endoplasmic reticulum lumen] (R-HSA-3238354) N4GlycoAsn-PalmS WNT7A [Golgi lumen] (R-HSA-3247778) N4GlycoAsn-PalmS WNT7A [extracellular region] (R-HSA-3247774) N4GlycoAsn-PalmS WNT7A [plasma membrane] (R-HSA-3247833)	0.623	3
IntAct:EBI-10171679 386682			0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:P22725 Wnt5a	11	Protein Wnt-5a [extracellular region] (R-MMU-517509) Wnt5a [endocytic vesicle membrane] (R-MMU-3781982) Wnt5a [extracellular exosome] (R-MMU-3781973) Wnt5a [clathrin-coated endocytic vesicle membrane] (R-MMU-5138454) N4GlycoAsn-PalmS Wnt5a [extracellular region] (R-MMU-3769351) N-glycosyl Wnt5a [endoplasmic reticulum lumen] (R-MMU-3238267) Wnt5a [endoplasmic reticulum lumen] (R-MMU-3238303) Wnt5a [endoplasmic reticulum lumen] (R-MMU-3238371) Wnt5a [Golgi lumen] (R-MMU-3247788) Wnt5a [plasma membrane] (R-MMU-3247799) Wnt5a [extracellular region] (R-MMU-3247777)	0.544	7
UniProt:P78560 CRADD	1	CRADD [cytosol] (R-HSA-5657970)	0.488	2

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