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PP2A (Aalpha:B55alpha:Calpha) [cytosol]
Stable Identifier
R-HSA-377182
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
ANKLE2 binds PP2A (Homo sapiens)
ANKLE2:PP2A [endoplasmic reticulum membrane] (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
PP2A dephosphorylates BANF1 (Homo sapiens)
ANKLE2:PP2A [endoplasmic reticulum membrane] (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Nonsense-Mediated Decay (NMD) (Homo sapiens)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Homo sapiens)
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
mRNA Cleaved by SMG6 [cytosol] (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
SMG6 hydrolyzes mRNA with premature termination codon (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
mRNA Cleaved by SMG6 [cytosol] (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
PP2A (Aalpha:B55alpha:Calpha) [cytosol] (Homo sapiens)
Participants
components
PPP2CA [cytosol]
(Homo sapiens)
PPP2R1A [cytosol]
(Homo sapiens)
PPP2R2A [cytosol]
(Homo sapiens)
Participates
as an output of
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Homo sapiens)
as an input of
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)
ANKLE2 binds PP2A (Homo sapiens)
as a component of
mRNA Cleaved by SMG6 [cytosol] (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
ANKLE2:PP2A [endoplasmic reticulum membrane] (Homo sapiens)
This entity regulates
Positively
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex
(Homo sapiens)
Inferred To
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Bos taurus)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Caenorhabditis elegans)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Canis familiaris)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Danio rerio)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Dictyostelium discoideum)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Drosophila melanogaster)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Gallus gallus)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Mus musculus)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Plasmodium falciparum)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Rattus norvegicus)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Saccharomyces cerevisiae)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Schizosaccharomyces pombe)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Sus scrofa)
PP2A (Aalpha:B55alpha:Calpha) [cytosol]
(Xenopus tropicalis)
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