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CTNNBIP1 [nucleoplasm]
Stable Identifier
R-HSA-3772388
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
ICAT
Locations in the PathwayBrowser for interactor UniProt:P14079 TAX
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Deactivation of the beta-catenin transactivating complex (Homo sapiens)
CTNNBIP1 binds beta-catenin (Homo sapiens)
CTNNBIP1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NSA3 CTNNBIP1
Gene Names
CTNNBIP1, ICAT
Chain
chain:1-81
Reference Genes
BioGPS Gene:56998 CTNNBIP1
COSMIC (genes):CTNNBIP1 CTNNBIP1
CTD Gene:56998 CTNNBIP1
dbSNP Gene:56998 CTNNBIP1
ENSEMBL:ENSG00000178585 CTNNBIP1
HGNC:16913 CTNNBIP1
KEGG Gene (Homo sapiens):56998 CTNNBIP1
Monarch:56998 CTNNBIP1
NCBI Gene:56998 CTNNBIP1
OMIM:607758 CTNNBIP1
UCSC:Q9NSA3 CTNNBIP1
Reference Transcript
RefSeq:XM_017001854.1 CTNNBIP1
RefSeq:NM_020248.2 CTNNBIP1
RefSeq:NM_001012329.1 CTNNBIP1
RefSeq:XM_017001853.1 CTNNBIP1
RefSeq:XM_017001855.1 CTNNBIP1
Other Identifiers
11716232_at
11716233_a_at
11716234_s_at
11745524_a_at
16681501
203081_at
2395964
2395966
2395967
2395968
2395981
2395982
2395987
2395991
2395999
2396000
2396007
2396008
39171_at
56998
7912283
A_23_P23584
A_33_P3286293
GE62276
GO:0000122
GO:0001658
GO:0002376
GO:0002528
GO:0003013
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006950
GO:0007165
GO:0007267
GO:0008013
GO:0008150
GO:0008283
GO:0009058
GO:0009952
GO:0016055
GO:0022607
GO:0030154
GO:0030178
GO:0030877
GO:0031333
GO:0032091
GO:0032991
GO:0034641
GO:0043226
GO:0043392
GO:0043433
GO:0045657
GO:0045669
GO:0048662
GO:0048856
GO:0060633
GO:0065003
GO:0070016
GO:0072201
ILMN_1688103
ILMN_2381168
PH_hs_0022281
TC01002187.hg
TC01005260.hg
g9910389_3p_at
Participant Of
hasComponent
CTNNBIP1:CTNNB1 [nucleoplasm]
input
CTNNBIP1 binds beta-catenin
Inferred To
Ctnnbip1 [nucleoplasm] (Mus musculus)
Ctnnbip1 [nucleoplasm] (Rattus norvegicus)
CTNNBIP1 [nucleoplasm] (Gallus gallus)
CTNNBIP1 [nucleoplasm] (Sus scrofa)
ctnnbip1 [nucleoplasm] (Danio rerio)
ctnnbip1 [nucleoplasm] (Xenopus tropicalis)
CLSTN1 [nucleoplasm] (Canis familiaris)
Cross References
RefSeq
XP_016857344.1
,
XP_016857342.1
,
XP_016857343.1
,
NP_064633.1
,
NP_001012329.1
OpenTargets
ENSG00000178585
GeneCards
Q9NSA3
HPA
ENSG00000178585-CTNNBIP1
Ensembl
ENSP00000383696
,
ENST00000377258
,
ENSP00000366474
,
ENSP00000366466
,
ENST00000377256
,
ENSP00000366468
,
ENSG00000178585
,
ENST00000400904
,
ENST00000377263
PRO
Q9NSA3
PDB
1M1E
,
1T08
,
1LUJ
Interactors (19)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35222 CTNNB1
33
CTNNB1 S45F [cytosol]
(R-HSA-4791268)
CTNNB1 S45A [cytosol]
(R-HSA-9663982)
CTNNB1 S45C [cytosol]
(R-HSA-9663983)
CTNNB1 S45Y [cytosol]
(R-HSA-9663975)
CTNNB1 S45N [cytosol]
(R-HSA-9663984)
CTNNB1 S45P [cytosol]
(R-HSA-4791272)
pT41,S45-CTNNB1 S37P [cytosol]
(R-HSA-9663981)
pT41,S45-CTNNB1 S37F [cytosol]
(R-HSA-4839621)
pT41,S45-CTNNB1 S37A [cytosol]
(R-HSA-4839619)
pT41,S45-CTNNB1 S37Y [cytosol]
(R-HSA-9663978)
pT41,S45-CTNNB1 S37C [cytosol]
(R-HSA-4839617)
pS37,T41,S45-CTNNB1 S33A [cytosol]
(R-HSA-9663976)
pS37,T41,S45-CTNNB1 S33T [cytosol]
(R-HSA-9663977)
pS37,T41,S45-CTNNB1 S33C [cytosol]
(R-HSA-4839630)
pS37,T41,S45-CTNNB1 S33F [cytosol]
(R-HSA-4839628)
pS37,T41,S45-CTNNB1 S33P [cytosol]
(R-HSA-4839626)
pS37,T41,S45-CTNNB1 S33Y [cytosol]
(R-HSA-4839625)
pS45-CTNNB1 T41N [cytosol]
(R-HSA-9663980)
pS45-CTNNB1 T41A [cytosol]
(R-HSA-4836868)
pS45-CTNNB1 T41I [cytosol]
(R-HSA-4839612)
Ub-K,p-Y-CTNNB1 [cytosol]
(R-HSA-8877006)
p-Y-CTNNB1 [cytosol]
(R-HSA-8876940)
p-S552-CTNNB1 [nucleoplasm]
(R-HSA-3134926)
p-S552-CTNNB1 [cytosol]
(R-HSA-3134933)
CTNNB1(116-376) [cytosol]
(R-HSA-202950)
CTNNB1(1-115) [cytosol]
(R-HSA-202930)
CTNNB1 [plasma membrane]
(R-HSA-9038440)
p-S45 CTNNB1 [cytosol]
(R-HSA-8942363)
p-T41,S45 CTNNB1 [cytosol]
(R-HSA-8942367)
p-S37,T41,S45, CTNNB1 [cytosol]
(R-HSA-8942369)
p-S33,S37,T41,S45 CTNNB1 [cytosol]
(R-HSA-8942374)
CTNNB1 [cytosol]
(R-HSA-448839)
CTNNB1 [nucleoplasm]
(R-HSA-3451168)
0.948
14
UniProt:P14923 JUP
5
JUP [ficolin-1-rich granule lumen]
(R-HSA-6801028)
JUP [cornified envelope]
(R-HSA-8847739)
JUP [extracellular region]
(R-HSA-6806309)
JUP [specific granule lumen]
(R-HSA-6799534)
JUP [plasma membrane]
(R-HSA-437260)
0.749
5
UniProt:Q02248 Ctnnb1
12
phospho-Ctnnb1 [cytosol]
(R-MMU-3134933)
phospho-Ctnnb1 [nucleoplasm]
(R-MMU-3134926)
Ctnnb1 [cytosol]
(R-MMU-202950)
Ctnnb1 [nucleoplasm]
(R-MMU-3451168)
Ctnnb1 [cytosol]
(R-MMU-448839)
phospho-Ctnnb1 [cytosol]
(R-MMU-8942374)
beta-catenin [cytosol]
(R-MMU-206225)
phospho-Ctnnb1 [cytosol]
(R-MMU-8942369)
phospho-Ctnnb1 [cytosol]
(R-MMU-8942367)
phospho-Ctnnb1 [cytosol]
(R-MMU-8942363)
Ctnnb1 [plasma membrane]
(R-MMU-9038440)
Ctnnb1 [cytosol]
(R-MMU-202930)
0.623
7
UniProt:Q9UL42 PNMA2
0.564
2
UniProt:P25054 APC
86
APC C1410* [cytosol]
(R-HSA-9666925)
APC R213* [cytosol]
(R-HSA-9666924)
APC K1310* [cytosol]
(R-HSA-9666926)
APC R499* [cytosol]
(R-HSA-9666927)
APC R1450* [cytosol]
(R-HSA-5251499)
APC G1357* [cytosol]
(R-HSA-9666940)
APC L1488* [cytosol]
(R-HSA-9666941)
APC S1400* [cytosol]
(R-HSA-9666942)
APC S1346* [cytosol]
(R-HSA-9666943)
APC R405* [cytosol]
(R-HSA-9666936)
APC S1281* [cytosol]
(R-HSA-9666937)
APC E1573* [cytosol]
(R-HSA-9666938)
APC R805* [cytosol]
(R-HSA-9666939)
APC R1386* [cytosol]
(R-HSA-9666932)
APC S1327* [cytosol]
(R-HSA-9666933)
APC E1209* [cytosol]
(R-HSA-9666934)
APC Q1469* [cytosol]
(R-HSA-9666935)
APC R564* [cytosol]
(R-HSA-9666928)
APC E1536* [cytosol]
(R-HSA-9666929)
APC G1288* [cytosol]
(R-HSA-9666930)
APC G1312* [cytosol]
(R-HSA-9666931)
APC R283* [cytosol]
(R-HSA-9666988)
APC Q1367* [cytosol]
(R-HSA-9666989)
APC E1353* [cytosol]
(R-HSA-9666990)
APC R332* [cytosol]
(R-HSA-9666991)
APC K993* [cytosol]
(R-HSA-9666984)
APC R876* [cytosol]
(R-HSA-9666985)
APC R302* [cytosol]
(R-HSA-9666986)
APC E1309* [cytosol]
(R-HSA-9666987)
APC Y935* [cytosol]
(R-HSA-9666980)
APC E1286* [cytosol]
(R-HSA-9666981)
APC Q1378* [cytosol]
(R-HSA-9666982)
APC R554* [cytosol]
(R-HSA-9666983)
APC S1356* [cytosol]
(R-HSA-9666976)
APC R232* [cytosol]
(R-HSA-9666977)
APC E1379* [cytosol]
(R-HSA-9666978)
APC E984* [cytosol]
(R-HSA-9666979)
APC R1114* [cytosol]
(R-HSA-9666996)
APC S1282* [cytosol]
(R-HSA-9666997)
APC Q1328* [cytosol]
(R-HSA-9666998)
APC E1295* [cytosol]
(R-HSA-9666992)
APC E1151* [cytosol]
(R-HSA-9666993)
APC E1322* [cytosol]
(R-HSA-9666994)
APC E1345* [cytosol]
(R-HSA-9666995)
APC K1308* [cytosol]
(R-HSA-9666956)
APC S1344* [cytosol]
(R-HSA-9666957)
APC E1577* [cytosol]
(R-HSA-9666958)
APC Q1127* [cytosol]
(R-HSA-9666959)
APC E1464* [cytosol]
(R-HSA-9666952)
APC E1317* [cytosol]
(R-HSA-9666953)
APC G1309Dfs*4 [cytosol]
(R-HSA-4791251)
APC W1049* [cytosol]
(R-HSA-9666954)
APC Q1429* [cytosol]
(R-HSA-9666955)
APC L1564* [cytosol]
(R-HSA-9666948)
APC Q1294* [cytosol]
(R-HSA-9666949)
APC K1363* [cytosol]
(R-HSA-9666950)
APC E1408* [cytosol]
(R-HSA-9666951)
APC E1284* [cytosol]
(R-HSA-9666944)
APC E1374* [cytosol]
(R-HSA-9666945)
APC Q767* [cytosol]
(R-HSA-9666946)
APC E941* [cytosol]
(R-HSA-9666947)
APC Q1303* [cytosol]
(R-HSA-9666972)
APC S943* [cytosol]
(R-HSA-9666973)
APC E1306* [cytosol]
(R-HSA-9666975)
APC S895* [cytosol]
(R-HSA-9666969)
APC S1315* [cytosol]
(R-HSA-9666970)
APC G1412* [cytosol]
(R-HSA-9666971)
APC Y1376* [cytosol]
(R-HSA-9666964)
APC Q886* [cytosol]
(R-HSA-9666965)
APC S1392* [cytosol]
(R-HSA-9666966)
APC S1539* [cytosol]
(R-HSA-9666967)
APC E1451* [cytosol]
(R-HSA-9666960)
APC E1397* [cytosol]
(R-HSA-9666961)
APC Q1406* [cytosol]
(R-HSA-9666962)
APC E1544* [cytosol]
(R-HSA-9666963)
APC F1197* [cytosol]
(R-HSA-5246655)
APC Q1338* [cytosol]
(R-HSA-5246654)
APC S811* [cytosol]
(R-HSA-5246652)
APC I1417 fs*2 [cytosol]
(R-HSA-5246651)
APC E1554* [cytosol]
(R-HSA-5246648)
APC(1-777) [cytosol]
(R-HSA-2976014)
APC(778-2843) [cytosol]
(R-HSA-2976013)
APC [cytosol]
(R-HSA-2976015)
p-ub-APC [cytosol]
(R-HSA-3009421)
K63polyUb-APC [cytosol]
(R-HSA-5246690)
APC [nucleoplasm]
(R-HSA-3361755)
0.564
2
UniProt:Q8N6Y0 USBP1
0.556
3
UniProt:Q4VC12 MSS51
0.556
3
IntAct:EBI-10171679 386682
0.556
3
UniProt:P0DPK4 NT2NC
0.556
3
UniProt:Q04864 REL
2
REL [nucleoplasm]
(R-HSA-1168585)
REL [cytosol]
(R-HSA-1168579)
0.556
3
UniProt:P26371 KRTAP5-9
1
KRTAP5-9 [cytosol]
(R-HSA-6810265)
0.556
3
UniProt:Q7Z4N8 P4HA3
1
P4HA3 [endoplasmic reticulum lumen]
(R-HSA-2980915)
0.556
3
UniProt:Q0VD86 INCA1
0.556
3
IntAct:EBI-22310722 CCSB ORF ID
0.556
3
UniProt:Q86W54-2 SPATA24
0.556
3
UniProt:P60409 KRTAP10-7
1
KRTAP10-7 [cytosol]
(R-HSA-6810279)
0.556
3
UniProt:Q9BRT9 GINS4
1
GINS4 [nucleoplasm]
(R-HSA-176963)
0.556
3
UniProt:P10275 AR
4
SUMO1-K386,520-AR [nucleoplasm]
(R-HSA-4090320)
PolyUb-AR [nucleoplasm]
(R-HSA-6782984)
AR [cytosol]
(R-HSA-5618082)
AR [nucleoplasm]
(R-HSA-446174)
0.532
4
UniProt:P14079 TAX
0.488
2
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