Reactome | pp-DVL1 [cytosol]

pp-DVL1 [cytosol]

Stable Identifier

R-HSA-3772396

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Dvl-1

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External Reference Information

External Reference

UniProt:O14640 DVL1

Gene Names

DVL1

Chain

chain:1-695

Reference Genes

BioGPS Gene:1855 DVL1

COSMIC (genes):DVL1 DVL1

CTD Gene:1855 DVL1

dbSNP Gene:1855 DVL1

ENSEMBL:ENSG00000107404 DVL1

ENSEMBL:ENSG00000107404.21 DVL1

HGNC:3084 DVL1

KEGG Gene (Homo sapiens):1855 DVL1

Monarch:1855 DVL1

NCBI Gene:1855 DVL1

OMIM:601365 DVL1

UCSC:O14640 DVL1

Reference Transcript

Other Identifiers

11723081_s_at

163_at

16680236

1855

203230_PM_at

203230_at

2391426

2391427

2391428

2391432

2391433

2391434

2391435

2391436

2391437

2391438

2391440

2391443

2391445

2391446

2391448

2391450

2391451

2391452

2391454

2391455

2391456

2391461

2391462

2391463

2391464

4044133

4044134

4044135

4044139

4044140

4044141

4044142

4044143

4044144

4044145

4044146

4044151

4044153

4044154

4044155

4044156

4044159

4044160

4044161

43392_at

45360_s_at

64927_at

7911506

A_23_P201342

A_23_P347432

GE61444

GO:0001505

GO:0001932

GO:0001933

GO:0001934

GO:0001947

GO:0003151

GO:0005109

GO:0005515

GO:0005737

GO:0005829

GO:0005856

GO:0005874

GO:0005886

GO:0006351

GO:0006355

GO:0006469

GO:0007010

GO:0007269

GO:0007409

GO:0007411

GO:0007528

GO:0008013

GO:0010976

GO:0014069

GO:0015630

GO:0016020

GO:0016055

GO:0016192

GO:0016328

GO:0019899

GO:0019901

GO:0021915

GO:0022007

GO:0022603

GO:0023052

GO:0030136

GO:0030154

GO:0030163

GO:0030424

GO:0030425

GO:0030426

GO:0031122

GO:0031267

GO:0031410

GO:0032091

GO:0032436

GO:0032880

GO:0034330

GO:0034504

GO:0035176

GO:0035372

GO:0035556

GO:0035567

GO:0036211

GO:0042802

GO:0043005

GO:0043025

GO:0043113

GO:0043197

GO:0043226

GO:0045202

GO:0045944

GO:0048668

GO:0048675

GO:0048813

GO:0048856

GO:0050808

GO:0050821

GO:0050877

GO:0060029

GO:0060070

GO:0060071

GO:0060134

GO:0060997

GO:0061024

GO:0071340

GO:0090103

GO:0090179

GO:0098685

GO:0098793

GO:0098978

GO:0098992

GO:0099054

GO:0099173

GO:0099175

GO:0150012

GO:1905386

GO:1990909

GO:2000300

GO:2000463

HMNXSV003011374

HMNXSV003031579

ILMN_1655632

ILMN_1657278

ILMN_1678564

ILMN_1783444

PH_hs_0004245

TC01002092.hg

U46461_at

g2291005_3p_at

Participates

as a member of

pp-DVL [cytosol] (Homo sapiens)

as a candidate of

pp-DVL [cytosol] (Homo sapiens)

Other forms of this molecule

p-S-DVL1 [cytosol]

DVL1 [cytosol]

ub-DVL1 [cytosol]

Inferred To

phospho-dsh-1 [cytosol] (Caenorhabditis elegans)

phospho-pp-DVL1 [cytosol] (Canis familiaris)

phospho-pp-DVL1 [cytosol] (Gallus gallus)

phospho-Dvl1 [cytosol] (Mus musculus)

phospho-Dvl1 [cytosol] (Rattus norvegicus)

phospho-dsh [cytosol] (Drosophila melanogaster)

phospho-DVL1 [cytosol] (Bos taurus)

phospho-DVL1 [cytosol] (Sus scrofa)

phospho-dvl1 [cytosol] (Danio rerio)

phospho-dvl1 [cytosol] (Xenopus tropicalis)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_004412.2, NP_001317240.1

OpenTargets

ENSG00000107404

GeneCards

O14640

HPA

ENSG00000107404-DVL1

Ensembl

ENSP00000368166, ENST00000378888, ENST00000378891, ENSP00000368169, ENSG00000107404

ZINC target

O14640

PRO

O14640

Pharos - Targets

O14640

Orphanet

23213

PDB

6TTK, 6LCA, 6LCB

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O70239	5	Axin1 [cytosol] (R-RNO-4641133) phospho-Axin1 [cytosol] (R-RNO-3640864) phospho-Axin1 [cytosol] (R-RNO-3640841) phospho-Axin1 [cytosol] (R-RNO-206040) Axin1 [cytosol] (R-RNO-195249)	0.796	12
UniProt:P49674 CSNK1E	2	CSNK1E [nucleoplasm] (R-HSA-421306) CSNK1E [cytosol] (R-HSA-205877)	0.639	6
UniProt:Q92997 DVL3	4	pp-DVL3 [cytosol] (R-HSA-3772400) p-DVL3 [cytosol] (R-HSA-201680) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.633	5
UniProt:P25054 APC	20	APC R213* [cytosol] (R-HSA-9666924) APC C1410* [cytosol] (R-HSA-9666925) APC K1310* [cytosol] (R-HSA-9666926) APC R499* [cytosol] (R-HSA-9666927) APC R1450* [cytosol] (R-HSA-5251499) APC G1357* [cytosol] (R-HSA-9666940) APC L1488* [cytosol] (R-HSA-9666941) APC S1400* [cytosol] (R-HSA-9666942) APC S1346* [cytosol] (R-HSA-9666943) APC R405* [cytosol] (R-HSA-9666936) APC S1281* [cytosol] (R-HSA-9666937) APC E1573* [cytosol] (R-HSA-9666938) APC R805* [cytosol] (R-HSA-9666939) APC R1386* [cytosol] (R-HSA-9666932) APC S1327* [cytosol] (R-HSA-9666933) APC E1209* [cytosol] (R-HSA-9666934) APC Q1469* [cytosol] (R-HSA-9666935) APC R564* [cytosol] (R-HSA-9666928) APC E1536* [cytosol] (R-HSA-9666929) APC G1288* [cytosol] (R-HSA-9666930)	0.623	6
UniProt:Q9EQC9 Cxxc4	1	Cxxc4 [cytosol] (R-RNO-5368460)	0.611	5
UniProt:Q6P3W7 SCYL2			0.544	4
UniProt:O14640 DVL1	4	pp-DVL1 [cytosol] (R-HSA-3772396) p-S-DVL1 [cytosol] (R-HSA-201700) DVL1 [cytosol] (R-HSA-201687) ub-DVL1 [cytosol] (R-HSA-4641157)	0.524	2
UniProt:Q9GZV5 WWTR1	3	p-S89-WWTR1 [cytosol] (R-HSA-2028665) WWTR1 [cytosol] (R-HSA-1629773) WWTR1 [nucleoplasm] (R-HSA-1629775)	0.524	2
UniProt:Q14186 TFDP1	1	TFDP1 [nucleoplasm] (R-HSA-68652)	0.463	3
UniProt:Q9Y4D1 DAAM1	1	DAAM1 [cytosol] (R-HSA-351052)	0.463	2

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