SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)

Stable Identifier
R-HSA-3777112
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

A portion of SOD1 is located in the mitochondrial intermembrane space (IMS) where it catalyzes the formation of oxygen (O2) and hydrogen peroxide (H2O2) from superoxide (O2.-) (He et al. 2011, Higgins et al. 2002, inferred from rat in Okado-Matsumoto and Fridovich 2001).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
superoxide dismutase activity of SOD1 dimer [mitochondrial intermembrane space]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Cross References
Rhea