Reactome | HDAC10 deacetylates histone

HDAC10 deacetylates histone

Stable Identifier

R-HSA-3782655

Type

Reaction [transition]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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HDAC10 is a class IIb HDAC subfamily member with greatest sequence similarity to HDAC6. Unlike HDAC6, HDAC10 is found in the nucleus. It is able to deacetylate acetylated histone H4 N-terminal peptides (Fischer et al. 2002, Guardiola & Yao 2002, Kao et al. 2002, Tong et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
11739383	Isolation and characterization of a novel class II histone deacetylase, HDAC10 Fischer, DD, Cai, R, Bhatia, U, Asselbergs, FA, Song, C, Terry, R, Trogani, N, Widmer, R, Atadja, P, Cohen, D	J. Biol. Chem.	2002