HDAC10 deacetylates histone

Stable Identifier
R-HSA-3782655
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

HDAC10 is a class IIb HDAC subfamily member with greatest sequence similarity to HDAC6. Unlike HDAC6, HDAC10 is found in the nucleus. It is able to deacetylate acetylated histone H4 N-terminal peptides (Fischer et al. 2002, Guardiola & Yao 2002, Kao et al. 2002, Tong et al. 2002).

Literature References
PubMed ID Title Journal Year
11739383 Isolation and characterization of a novel class II histone deacetylase, HDAC10 J. Biol. Chem. 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
histone deacetylase activity of HDAC10 [nucleoplasm]
Physical Entity
Activity
Orthologous Events