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What is Reactome ?
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Adenylate cyclase [plasma membrane]
Stable Identifier
R-HSA-379053
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to mechanical stimuli (Homo sapiens)
Response of endothelial cells to shear stress (Homo sapiens)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Homo sapiens)
Activated Adenylate cyclase catalyses cAMP synthesis (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
FCGR3A-mediated IL10 synthesis (Homo sapiens)
Adenylate cyclase produces cAMP (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Glucagon signaling in metabolic regulation (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
PKA activation in glucagon signalling (Homo sapiens)
Activated Adenylate cyclase catalyses cAMP synthesis (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
GABA receptor activation (Homo sapiens)
GABA B receptor activation (Homo sapiens)
Activation of GABAB receptors (Homo sapiens)
Adenylate cyclase inhibitory pathway (Homo sapiens)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase increases the GTPase activity of Gi alpha (Homo sapiens)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Dissociation of the Gi alpha:G olf complex (Homo sapiens)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
PKA-mediated phosphorylation of CREB (Homo sapiens)
PKA activation (Homo sapiens)
Adenylate cyclase produces cAMP (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
Adenylate cyclase activating pathway (Homo sapiens)
Adenylate cyclase converts ATP into cyclic AMP (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Galpha-olf:GTP binds to adenylate cyclase and activates it (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase inhibitory pathway (Homo sapiens)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase increases the GTPase activity of Gi alpha (Homo sapiens)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Dissociation of the Gi alpha:G olf complex (Homo sapiens)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
PKA-mediated phosphorylation of CREB (Homo sapiens)
PKA activation (Homo sapiens)
Adenylate cyclase produces cAMP (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
GPER1 signaling (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (z) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (z) inhibits adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Aquaporin-mediated transport (Homo sapiens)
Vasopressin regulates renal water homeostasis via Aquaporins (Homo sapiens)
Activated Adenylate cyclase catalyses cAMP synthesis (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Adenylate cyclase [plasma membrane] (Homo sapiens)
Participants
members
ADCY2 [plasma membrane]
(Homo sapiens)
ADCY3 [plasma membrane]
(Homo sapiens)
ADCY4 [plasma membrane]
(Homo sapiens)
ADCY6 [plasma membrane]
(Homo sapiens)
ADCY7 [plasma membrane]
(Homo sapiens)
ADCY9 [plasma membrane]
(Homo sapiens)
ADCY1 [plasma membrane]
(Homo sapiens)
ADCY5 [plasma membrane]
(Homo sapiens)
ADCY8 [plasma membrane]
(Homo sapiens)
Participates
as a component of
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
Inferred To
Adenylate cyclase [plasma membrane]
(Bos taurus)
Adenylate cyclase [plasma membrane]
(Caenorhabditis elegans)
Adenylate cyclase [plasma membrane]
(Canis familiaris)
Adenylate cyclase [plasma membrane]
(Danio rerio)
Adenylate cyclase [plasma membrane]
(Dictyostelium discoideum)
Adenylate cyclase [plasma membrane]
(Drosophila melanogaster)
Adenylate cyclase [plasma membrane]
(Gallus gallus)
Adenylate cyclase [plasma membrane]
(Mus musculus)
Adenylate cyclase [plasma membrane]
(Rattus norvegicus)
Adenylate cyclase [plasma membrane]
(Sus scrofa)
Adenylate cyclase [plasma membrane]
(Xenopus tropicalis)
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