Reactome | KARS [cytosol]

KARS [cytosol]

Stable Identifier

R-HSA-379568

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Lysyl-tRNA synthetase

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15046 KARS1

Gene Names

KARS1, KARS, KIAA0070

Chain

initiator methionine:1, chain:2-597

Reference Genes

BioGPS Gene:3735 KARS1

CTD Gene:3735 KARS1

dbSNP Gene:3735 KARS1

ENSEMBL:ENSG00000065427 KARS

HGNC:6215 KARS1

KEGG Gene (Homo sapiens):3735 KARS1

Monarch:3735 KARS1

NCBI Gene:3735 KARS1

OMIM:601421 KARS1

UCSC:Q15046 KARS1

Reference Transcript

Other Identifiers

0006550368

11733807_a_at

16828514

18671106

18671107

18671108

18671109

18671110

18671111

18671112

18671113

18671114

18671115

18671116

18671117

18671118

18671119

18671120

18671121

18671122

200079_PM_s_at

200079_s_at

200840_at

34336_at

3699758

3699759

3699760

3699762

3699764

3699765

3699766

3699767

3699768

3699769

3699771

3699773

3699774

3699776

3699779

3699780

3699781

3699782

3699786

3699787

3699790

3735

7892618

7892953

7893113

7893248

7893362

7893477

7893549

7893933

7894238

7894331

7894737

7895038

7895221

7895264

7895419

7895578

7895770

7895817

7896201

7896362

8002919

A_23_P152487

D31890_at

GE57175

GO:0000049

GO:0000166

GO:0000187

GO:0002276

GO:0002376

GO:0002720

GO:0003674

GO:0003676

GO:0003723

GO:0003877

GO:0004812

GO:0004824

GO:0005515

GO:0005524

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005737

GO:0005739

GO:0005759

GO:0005829

GO:0005886

GO:0006399

GO:0006412

GO:0006418

GO:0006430

GO:0006464

GO:0006520

GO:0006950

GO:0007165

GO:0008033

GO:0008150

GO:0008283

GO:0008285

GO:0009058

GO:0010165

GO:0010759

GO:0015966

GO:0016020

GO:0016032

GO:0016597

GO:0016740

GO:0016779

GO:0016874

GO:0017101

GO:0032991

GO:0033209

GO:0034641

GO:0040011

GO:0042802

GO:0042803

GO:0043032

GO:0043167

GO:0043226

GO:0044281

GO:0044403

GO:0045893

GO:0048870

GO:0070371

GO:0070374

GO:1900017

GO:1900745

GO:1905050

ILMN_1777584

PH_hs_0000387

TC16001284.hg

TC16001967.hg

g11095908_3p_a_at

Participant Of

hasComponent

KARS homodimer [cytosol]

Other forms of this molecule

KARS [mitochondrial matrix]

Cross References

RefSeq

NP_001123561.1, NP_005539.1

OpenTargets

ENSG00000065427

ZINC - Substances

SYK_HUMAN

ZINC target

Q15046

ZINC - Biogenic

SYK_HUMAN

PRO

Q15046

PDB

6ILD, 4YCU, 4DPG, 4YCW, 3BJU, 6ILH, 6CHD

GeneCards

Q15046

HPA

ENSG00000065427-KARS

Ensembl

ENST00000302445, ENSP00000303043, ENST00000319410, ENSG00000065427, ENSP00000325448

ZINC - Predictions - Purchasable

SYK_HUMAN

Orphanet

20149

HMDB Protein

HMDBP00613

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00441 SOD1	5	2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [extracellular region] (R-HSA-350705) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [cytosol] (R-HSA-3299726)	0.556	3

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