Reactome | RARS [cytosol]

RARS [cytosol]

Stable Identifier

R-HSA-379586

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Arginyl-tRNA synthetase

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P54136 RARS1

Gene Names

RARS1, RARS

Chain

chain:1-660

Reference Genes

BioGPS Gene:5917 RARS1

CTD Gene:5917 RARS1

dbSNP Gene:5917 RARS1

ENSEMBL:ENSG00000113643 RARS

ENSEMBL_homo_sapiens_GENE:ENSG00000113643.9 RARS1

HGNC:9870 RARS1

KEGG Gene (Homo sapiens):5917 RARS1

Monarch:5917 RARS1

NCBI Gene:5917 RARS1

OMIM:107820 RARS1

UCSC:P54136 RARS1

Reference Transcript

RefSeq:NM_002887.3 RARS1

Other Identifiers

11729103_a_at

11744879_a_at

16992026

201330_PM_at

201330_at

2839672

2839673

2839676

2839677

2839680

2839682

2839684

2839687

2839690

2839691

2839692

2839693

2839697

2839698

2839699

2839700

2839701

2839702

549_at

5917

71684_at

8109802

A_14_P121117

A_23_P69988

GE62906

GO:0000049

GO:0000166

GO:0003723

GO:0003824

GO:0004812

GO:0004814

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0006399

GO:0006412

GO:0006418

GO:0006420

GO:0006520

GO:0016020

GO:0016874

GO:0017101

GO:0034618

GO:0043226

GO:0045296

GO:0070062

GO:0140098

HMNXSV003008341

ILMN_1751378

PH_hs_0010700

S80343_at

TC05000919.hg

Participates

as a component of

Inferred To

argS2 [cytosol] (Dictyostelium discoideum)

RARS [cytosol] (Bos taurus)

RARS [cytosol] (Drosophila melanogaster)

RARS [cytosol] (Gallus gallus)

RARS [cytosol] (Mus musculus)

RARS [cytosol] (Rattus norvegicus)

RARS1 [cytosol] (Canis familiaris)

RARS1 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_002878.2

OpenTargets

ENSG00000113643

ZINC - Substances

SYRC_HUMAN

ZINC target

P54136

PRO

P54136

PDB

4Q2T, 4Q2Y, 4ZAJ, 4Q2X, 4R3Z

IntEnz

6.1.1.19

HPA

ENSG00000113643-RARS1

GeneCards

P54136

Ensembl

ENSP00000231572, ENST00000231572, ENSG00000113643

Pharos - Targets

P54136

Orphanet

23433

ZINC - Predictions - Purchasable

SYRC_HUMAN

HMDB Protein

HMDBP00591

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96K83 ZNF521	1	ZNF521 [nucleoplasm] (R-HSA-3222324)	0.556	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	9

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