Reactome | VARS2 [mitochondrial matrix]

VARS2 [mitochondrial matrix]

Stable Identifier

R-HSA-379626

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Valyl-tRNA synthetase 2

Locations in the PathwayBrowser for interactor UniProt:Q9P2A4 ABI3

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External Reference Information

External Reference

UniProt:Q5ST30 VARS2

Gene Names

VARS2, KIAA1885, VARS2L, VARSL

Chain

transit peptide:1-26, chain:27-1063

Reference Genes

BioGPS Gene:57176 VARS2

COSMIC (genes):VARS2 VARS1

CTD Gene:57176 VARS2

dbSNP Gene:57176 VARS2

ENSEMBL:ENSG00000137411 VARS2

HGNC:21642 VARS2

KEGG:hsa:57176 VARS2

Monarch:57176 VARS2

NCBI Gene:57176 VARS2

OMIM:612802 VARS2

UCSC:Q5ST30 VARS2

Reference Transcript

Cross References

ENSEMBL

ENSP00000316092, ENSG00000223494, ENSP00000485818, ENSP00000400867, ENSP00000502585, ENST00000546854, ENSP00000446839, ENSG00000137411, ENST00000541562, ENST00000625423, ENST00000676266, ENST00000415079, ENST00000321897, ENSP00000441000

OpenTargets

ENSG00000137411

GeneCards

VARS2

HPA

ENSG00000137411-VARS2

PRO

Q5ST30

Pharos - Targets

Q5ST30

HMDB Protein

HMDBP07421

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60504 SORBS3	1	SORBS3 [cytosol] (R-HSA-445805)	0.556	3
UniProt:Q8IZP0-5 ABI1			0.556	3
UniProt:Q9P2A4 ABI3			0.556	3
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.556	3
UniProt:Q9NYB9-2 ABI2			0.556	3
UniProt:O75251 NDUFS7	1	NDUFS7 [mitochondrial matrix] (R-HSA-6788521)	0.527	3
UniProt:O95861 BPNT1	1	BPNT1 [cytosol] (R-HSA-176573)	0.527	2
UniProt:Q9BZX2 UCK2	1	UCK 2 [cytosol] (R-HSA-66871)	0.527	3

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