threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate

Stable Identifier
R-HSA-380002
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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TARS (cytosolic threonyl tRNA synthetase) catalyzes the reaction of threonine, tRNA(Thr), and ATP to form Thr-tRNA(Thr), AMP, and pyrophosphate. The enzyme, a class II tRNA synthetase, is a homodimer (Pan et al. 1982).

Literature References
PubMed ID Title Journal Year
7118399 Purification and subunit structure studies of human placental threonyl-tRNA synthetase

Pan, F, Lee, HH, Pai, SH, Lo, KY

Int J Pept Protein Res 1982
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
threonine-tRNA ligase activity of TARS dimer [cytosol]
Physical Entity
Activity
Authored
Reviewed
Created