tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate

Stable Identifier
R-HSA-380170
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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YARS2 (mitochondrial tyrosyl tRNA synthetase) catalyzes the reaction of tyrosine, mitochondrial tRNA(Tyr), and ATP to form Tyr-tRNA(Tyr), AMP, and pyrophosphate. The enzyme, a class I tRNA synthetase, is a homodimer (Bonnefond et al. 2005).

Literature References
PubMed ID Title Journal Year
15779907 Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS

Bonnefond, L, Fender, A, Rudinger-Thirion, J, Giege, R, Florentz, C, Sissler, M

Biochemistry 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
tyrosine-tRNA ligase activity of YARS2 dimer [mitochondrial matrix]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created