valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate

Stable Identifier
R-HSA-380199
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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VARS2 (mitochondrial valyl tRNA synthetase) catalyzes the reaction of valine, mitochondrial tRNA(val), and ATP to form Val-tRNA(Val), AMP, and pyrophosphate. The VARS2 gene has been identified by computational analysis of the human genome sequence; its function has been inferred from those of the biochemically characterized mitochondrial aspartyl and tyrosyl tRNA synthetases (Bonnefond et al. 2005).

Participants
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Catalyst Activity
Catalyst Activity
Title
valine-tRNA ligase activity of VARS2 [mitochondrial matrix]
Physical Entity
Activity
Inferred From
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Created