threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate

Stable Identifier
R-HSA-380201
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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TARS2 (mitochondrial threonyl tRNA synthetase) catalyzes the reaction of threonine, mitochondrial tRNA(Thr), and ATP to form Thr-tRNA(Thr), AMP, and pyrophosphate. The TARS2 gene has been identified by computational analysis of the human genome sequence; its function has been inferred from those of the biochemically characterized mitochondrial aspartyl and tyrosyl tRNA synthetases (Bonnefond et al. 2005).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
threonine-tRNA ligase activity of TARS2(1-?) [mitochondrial matrix]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created