tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate

Stable Identifier
R-HSA-380222
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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WARS2 (mitochondrial tryptophanyl tRNA synthetase) catalyzes the reaction of tryptophan, mitochondrial tRNA(Trp), and ATP to form Trp-tRNA(Trp), AMP, and pyrophosphate. The enzyme is a class I tRNA synthetase (Jorgensen et al. 2000).

Literature References
PubMed ID Title Journal Year
10828066 Identification and characterization of human mitochondrial tryptophanyl-tRNA synthetase

Jorgensen, R, Sogaard, TM, Rossing, AB, Martensen, PM, Justesen, J

J Biol Chem 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
tryptophan-tRNA ligase activity of WARS2 [mitochondrial matrix]
Physical Entity
Activity
Authored
Reviewed
Created