asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate

Stable Identifier
R-HSA-380227
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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NARS2 (mitochondrial asparaginyl tRNA synthetase) catalyzes the reaction of asparagine, mitochondrial tRNA(Asn), and ATP to form Asn-tRNA(Asn), AMP, and pyrophosphate. The NARS2 gene has been identified by computational analysis of the human genome sequence; its function has been inferred from those of the biochemically characterized mitochondrial aspartyl and tyrosyl tRNA synthetases (Bonnefond et al. 2005).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
asparagine-tRNA ligase activity of NARS2 [mitochondrial matrix]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created