serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate

Stable Identifier
R-HSA-380239
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

SARS2 (mitochondrial seryl tRNA synthetase) catalyzes the reaction of serine, mitochondrial tRNA(Ser), and ATP to form Ser-tRNA(Ser), AMP, and pyrophosphate. SARS2 is a class II tRNA synthetase inferred from the biochemical properties of its bovine homologue to function as a dimer (Yokogawa et al. 2000).

Literature References
PubMed ID Title Journal Year
10764807 Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase

Yokogawa, T, Shimada, N, Takeuchi, N, Benkowski, L, Suzuki, T, Omori, A, Ueda, T, Nishikawa, K, Spremulli, LL, Watanabe, K

J Biol Chem 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
serine-tRNA ligase activity of SARS2 dimer [mitochondrial matrix]
Physical Entity
Activity
Authored
Reviewed
Created