serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate

Stable Identifier
R-HSA-380239
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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SARS2 (mitochondrial seryl tRNA synthetase) catalyzes the reaction of serine, mitochondrial tRNA(Ser), and ATP to form Ser-tRNA(Ser), AMP, and pyrophosphate. SARS2 is a class II tRNA synthetase inferred from the biochemical properties of its bovine homologue to function as a dimer (Yokogawa et al. 2000).
Literature References
PubMed ID Title Journal Year
10764807 Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase

Suzuki, T, Benkowski, L, Spremulli, LL, Omori, A, Yokogawa, T, Nishikawa, K, Takeuchi, N, Shimada, N, Watanabe, K, Ueda, T

J Biol Chem 2000
Participants
Participates
Catalyst Activity

serine-tRNA ligase activity of SARS2 dimer [mitochondrial matrix]

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