glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate

Stable Identifier
R-HSA-380241
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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QARS (mitochondrial glutaminyl tRNA synthetase) catalyzes the reaction of glutamine, tRNA(Gln), and ATP to form Gln-tRNA(Gln), AMP, and pyrophosphate. The enzyme is a class I tRNA synthetase. The same gene encodes both the cytosolic and mitochondrial QARS enzymes (Lamour et al. 1994).

Literature References
PubMed ID Title Journal Year
8078941 Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer

Lamour, V, Quevillon, S, Diriong, S, N'Guyen, VC, Lipinski, M, Mirande, M

Proc Natl Acad Sci U S A 1994
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
glutamine-tRNA ligase activity of QARS [mitochondrial matrix]
Physical Entity
Activity
Authored
Reviewed
Created