Recruitment of mitotic centrosome proteins and complexes

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R-HSA-380270
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Pathway
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Homo sapiens
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5/5
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The mitotic spindle becomes established once centrosomes have migrated to opposite poles and the nuclear envelope has broken down. During this stage, interphase centrosomes mature into mitotic centrosomes recruiting additional gamma TuRC complexes and acquiring mitosis-associated centrosomal proteins including NuMA, Plk1 and CDK11p58 (reviewed in Schatten 2008; Raynaud-Messina and Merdes 2007).
Literature References
PubMed ID Title Journal Year
18437411 The mammalian centrosome and its functional significance

Schatten, H

Histochem Cell Biol 2008
17178454 Gamma-tubulin complexes and microtubule organization

Raynaud-Messina, B, Merdes, A

Curr Opin Cell Biol 2007
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