Loss of C-Nap-1 from centrosomes

Stable Identifier
R-HSA-380294
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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The centrosomal protein C-Nap1 is thought to play an important role in centrosome cohesion during interphase (Fry et al.,1998). At the onset of mitosis, when centrosomes separate to form the bipolar spindle, C-Nap1 dissociates (Mayor et al., 2000). Dissociation of C-Nap1 from mitotic centrosomes appears to be regulated by phosphorylation (Mayor et al. 2002).

Literature References
PubMed ID Title Journal Year
11076968 The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion

Mayor, T, Stierhof, YD, Tanaka, K, Fry, AM, Nigg, EA

J Cell Biol 2000
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