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CSNK1D [cytosol]
Stable Identifier
R-HSA-380315
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Casein kinase I, delta
Icon
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Prometaphase (Homo sapiens)
Recruitment of NuMA to mitotic centrosomes (Homo sapiens)
Association of NuMA with microtubules (Homo sapiens)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Homo sapiens)
Mature centrosome:nucleated microtubules [cytosol] (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Translocation of NuMA to the centrosomes (Homo sapiens)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
AURKA Activation by TPX2 (Homo sapiens)
TPX2 binds AURKA at centrosomes (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
TPX2 promotes AURKA autophosphorylation (Homo sapiens)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Centrosome maturation (Homo sapiens)
Loss of proteins required for interphase microtubule organization from the centrosome (Homo sapiens)
Loss of C-Nap-1 from centrosomes (Homo sapiens)
cNAP-1 depleted centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Loss of Nlp from mitotic centrosomes (Homo sapiens)
Dissociation of Phospho-Nlp from the centrosome (Homo sapiens)
Nlp-depleted centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
centrosome containing phosphorylated Nlp [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Plk1-mediated phosphorylation of Nlp (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
centrosome containing phosphorylated Nlp [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Recruitment of mitotic centrosome proteins and complexes (Homo sapiens)
Recruitment of CDK11p58 to the centrosomes (Homo sapiens)
Centrosomes containing recruited CDK11p58 [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Recruitment of Plk1 to centrosomes (Homo sapiens)
Centrosome associated Plk1 [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Homo sapiens)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Regulation of PLK1 Activity at G2/M Transition (Homo sapiens)
AJUBA binds centrosome-associated AURKA (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Centrosome:AURKA:AJUBA [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
AJUBA facilitates AURKA autophosphorylation (Homo sapiens)
Centrosome:AURKA:AJUBA [cytosol] (Homo sapiens)
Centrosome:AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
AURKA phosphorylates PLK1 (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
BORA binds PLK1 and AURKA (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Homo sapiens)
Centrosome:p-T288-AURKA [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Circadian Clock (Homo sapiens)
CRY:PER:Kinase complex translocates to the nucleus (Homo sapiens)
p-CRY:p-PER:Kinase [cytosol] (Homo sapiens)
CSNK1E,CSNK1D [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
CSNK1E,CSNK1D phosphorylate CRY and PER proteins (Homo sapiens)
CRY:PER:Kinase [cytosol] (Homo sapiens)
CSNK1E,CSNK1D [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
CSNK1E,CSNK1D [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
p-CRY:p-PER:Kinase [cytosol] (Homo sapiens)
CSNK1E,CSNK1D [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Formation of CRY:PER:Kinase complex (Homo sapiens)
CRY:PER:Kinase [cytosol] (Homo sapiens)
CSNK1E,CSNK1D [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
CSNK1E,CSNK1D [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Anchoring of the basal body to the plasma membrane (Homo sapiens)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
mother centriole:C2CD3 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
mother centriole:C2CD3 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
C2CD3 binds the mother centriole (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
mother centriole:C2CD3 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
CP110 and CEP97 dissociate from the centriole (Homo sapiens)
basal body [cytosol] (Homo sapiens)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
mother centriole:C2CD3 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
MARK4 binds ODF2 in the centriole (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
mother centriole:C2CD3 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
mother centriole:C2CD3 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
RAB3IP stimulates nucleotide exchange on RAB8A (Homo sapiens)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Recruitment of transition zone proteins (Homo sapiens)
basal body [cytosol] (Homo sapiens)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
basal body:transition zone proteins [cytosol] (Homo sapiens)
basal body [cytosol] (Homo sapiens)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
The distal appendage proteins recruit TTBK2 (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
mother centriole:C2CD3 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Homo sapiens)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Homo sapiens)
mother centriole:C2CD3 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
CSNK1D [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48730 CSNK1D
Gene Names
CSNK1D, HCKID
Chain
chain:1-415
Reference Genes
COSMIC (genes):CSNK1D CSNK1D
dbSNP Gene:1453 CSNK1D
ENSEMBL:ENSG00000141551 CSNK1D
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Homo sapiens)
mother centriole [cytosol] (Homo sapiens)
Nlp-depleted centrosome [cytosol] (Homo sapiens)
centrosome containing phosphorylated Nlp [cytosol] (Homo sapiens)
cNAP-1 depleted centrosome [cytosol] (Homo sapiens)
centrosome [cytosol] (Homo sapiens)
as an output of
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)
as a candidate of
CSNK1E,CSNK1D [cytosol] (Homo sapiens)
This entity regulates
Positively
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol
(Homo sapiens)
Other forms of this molecule
CSNK1D [nucleoplasm]
CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane]
Inferred To
Csnk1d [cytosol]
(Mus musculus)
CSNK1D [cytosol]
(Bos taurus)
CSNK1D [cytosol]
(Canis familiaris)
CSNK1D [cytosol]
(Gallus gallus)
CSNK1D [cytosol]
(Rattus norvegicus)
CSNK1D [cytosol]
(Sus scrofa)
CSNK1D [cytosol]
(Xenopus tropicalis)
Interactors (36)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O15055 PER2
4
Ub-p-S-PER2 [cytosol]
(R-HSA-517835)
PER2 [cytosol]
(R-HSA-400399)
p-S-PER2 [nucleoplasm]
(R-HSA-3325591)
p-S-PER2 [cytosol]
(R-HSA-400331)
0.756
6
UniProt:Q14C86 GAPVD1
1
GAPVD1 [cytosol]
(R-HSA-8871123)
0.669
4
UniProt:P23508 CRCM
0.669
5
UniProt:Q5T7W0 ZN618
0.666
4
UniProt:Q92997 DVL3
4
pp-DVL3 [cytosol]
(R-HSA-3772400)
p-DVL3 [cytosol]
(R-HSA-201680)
DVL3 [cytosol]
(R-HSA-201678)
ub-DVL3 [cytosol]
(R-HSA-4652688)
0.666
4
UniProt:Q6ZRV2 FA83H
0.643
5
UniProt:P48729 CSNK1A1
2
CSNK1A1 [cilium]
(R-HSA-5632507)
CSNK1A1 [cytosol]
(R-HSA-195263)
0.643
3
UniProt:Q96LR2 LURA1
0.61
4
UniProt:Q00987 MDM2
11
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
MDM2 [cytosol]
(R-HSA-198644)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
MDM2 [plasma membrane]
(R-HSA-416843)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
monoSUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
0.61
6
UniProt:Q15154 PCM1
1
PCM1 [cytosol]
(R-HSA-380308)
0.569
3
UniProt:Q9C026 TRIM9
1
TRIM9 [cytosol]
(R-HSA-976054)
0.556
3
UniProt:Q6PGQ1 DRIC1
0.556
3
UniProt:O75382 TRIM3
1
TRIM3 [cytosol]
(R-HSA-5624344)
0.556
3
UniProt:O60447 EVI5
0.556
3
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.556
3
UniProt:Q9H2S9 IKZF4
0.556
3
UniProt:Q96BR9 ZBT8A
0.556
3
UniProt:Q9P286 PAK5
2
PAK5 [cytosol]
(R-HSA-428459)
PAK7 [plasma membrane]
(R-HSA-211555)
0.556
3
UniProt:Q9BRK4 LZTS2
0.556
3
UniProt:Q49A88-3 CCDC14
0.556
3
UniProt:Q99996 AKAP9
3
AKAP9(1-1118)-BRAF(381-766) fusion [cytosol]
(R-HSA-6802267)
AKAP9(1-1118)-p-BRAF(381-766) fusion [cytosol]
(R-HSA-6802514)
AKAP9 [cytosol]
(R-HSA-380260)
0.527
3
UniProt:Q5T0W9 FAM83B
1
FAM83B [cytosol]
(R-HSA-9715184)
0.527
3
UniProt:Q7Z5H3 ARHGAP22
1
ARHGAP22 [cytosol]
(R-HSA-200762)
0.527
2
UniProt:Q8TC76 F110B
0.527
2
UniProt:Q9Y343 SNX24
0.527
3
UniProt:Q8WVL7 ANR49
0.527
2
UniProt:Q6PEV8 F199X
0.527
2
UniProt:Q9H4H8 FAM83D
1
FAM83D [cytosol]
(R-HSA-9852722)
0.527
2
UniProt:P49674 CSNK1E
2
CSNK1E [cytosol]
(R-HSA-205877)
CSNK1E [nucleoplasm]
(R-HSA-421306)
0.527
2
UniProt:Q7Z7G8 VP13B
0.527
3
UniProt:Q9H9R9 DBND1
0.527
2
UniProt:Q49AN0 CRY2
4
p-S-CRY2 [cytosol]
(R-HSA-400305)
p-S-CRY2 [nucleoplasm]
(R-HSA-400328)
CRY2 [cytosol]
(R-HSA-400255)
Ub-p-S-CRY2 [nucleoplasm]
(R-HSA-517935)
0.527
3
UniProt:Q9UIM3 FKBPL
1
FKBPL [cytosol]
(R-HSA-8852374)
0.527
2
UniProt:O15534 PER1
4
p-S-PER1 [cytosol]
(R-HSA-400310)
p-S-PER1 [nucleoplasm]
(R-HSA-3325590)
PER1 [cytosol]
(R-HSA-400373)
Ub-p-S-PER1 [cytosol]
(R-HSA-517831)
0.527
3
UniProt:Q16526 CRY1
4
Ub-p-S-CRY1 [nucleoplasm]
(R-HSA-517931)
CRY1 [cytosol]
(R-HSA-400247)
p-S-CRY1 [nucleoplasm]
(R-HSA-400340)
p-S-CRY1 [cytosol]
(R-HSA-400270)
0.527
3
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.527
2
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