Reactome | SYN1 [clathrin-sculpted monoamine transport vesicle membrane]

SYN1 [clathrin-sculpted monoamine transport vesicle membrane]

Stable Identifier

R-HSA-380577

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

clathrin-sculpted monoamine transport vesicle membrane

Synonyms

Synapsin I

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P17600 SYN1

Gene Names

SYN1

Chain

chain:1-705

Reference Genes

BioGPS Gene:6853 SYN1

COSMIC (genes):SYN1 SYN1

CTD Gene:6853 SYN1

dbSNP Gene:6853 SYN1

ENSEMBL:ENSG00000008056 SYN1

HGNC:11494 SYN1

KEGG Gene (Homo sapiens):6853 SYN1

Monarch:6853 SYN1

NCBI Gene:6853 SYN1

OMIM:313440 SYN1

UCSC:P17600 SYN1

Reference Transcript

Other Identifiers

0004010577

0004610692

11726133_a_at

1553264_a_at

17110447

221914_at

32923_r_at

4007127

4007128

4007129

4007130

4007131

4007132

4007134

4007135

4007136

4007137

4007138

4007139

4007140

4007141

4007142

4007149

4007151

4007153

4007154

4007158

4007159

4007160

4007161

47050_at

6853

8172317

A_23_P33847

A_23_P500824

GE60549

GE80390

GO:0000228

GO:0000795

GO:0003674

GO:0003779

GO:0005215

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0005737

GO:0005794

GO:0005829

GO:0005856

GO:0006810

GO:0007267

GO:0007268

GO:0007269

GO:0008021

GO:0008092

GO:0008150

GO:0014069

GO:0016192

GO:0019899

GO:0019901

GO:0030054

GO:0030154

GO:0030424

GO:0030425

GO:0030672

GO:0031410

GO:0034330

GO:0042802

GO:0043167

GO:0043226

GO:0043229

GO:0045202

GO:0046928

GO:0048306

GO:0048666

GO:0048786

GO:0048856

GO:0050808

GO:0097091

GO:0098685

GO:0098693

GO:0098793

GO:0098850

GO:0098993

GO:0099504

GO:2000300

HMNXSV003007635

Hs.225936.0.S2_3p_at

Hs2.225936.1.S1_3p_s_at

ILMN_1660693

ILMN_1725337

ILMN_1783837

ILMN_2407703

M58378_cds1_at

PH_hs_0035705

TC0X000997.hg

Participates

as a candidate of

Synapsin [clathrin-sculpted monoamine transport vesicle membrane] (Homo sapiens)

Other forms of this molecule

SYN1 [clathrin-sculpted glutamate transport vesicle membrane]

Inferred To

Syn [clathrin-sculpted monoamine transport vesicle membrane] (Drosophila melanogaster)

SYN1 [clathrin-sculpted monoamine transport vesicle membrane] (Bos taurus)

SYN1 [clathrin-sculpted monoamine transport vesicle membrane] (Sus scrofa)

Syn1 [clathrin-sculpted monoamine transport vesicle membrane] (Mus musculus)

Syn1 [clathrin-sculpted monoamine transport vesicle membrane] (Rattus norvegicus)

snn-1 [clathrin-sculpted monoamine transport vesicle membrane] (Caenorhabditis elegans)

syn1 [clathrin-sculpted monoamine transport vesicle membrane] (Danio rerio)

Cross References

RefSeq

NP_598006.1, NP_008881.2

OpenTargets

ENSG00000008056

GeneCards

P17600

HPA

ENSG00000008056-SYN1

Ensembl

ENSG00000008056, ENST00000340666, ENSP00000295987, ENSP00000343206, ENST00000295987

PRO

P17600

Orphanet

15573

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	59	p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541) p-6Y-EGFR A289V [plasma membrane] (R-HSA-1996334) p-6Y-EGFR T263P [plasma membrane] (R-HSA-1996336) p-6Y-EGFR G598V [plasma membrane] (R-HSA-1996339) p-6Y-EGFR R108K [plasma membrane] (R-HSA-1996338) p-6Y-EGFR A289T [plasma membrane] (R-HSA-1996341) p-6Y-EGFR G719C [plasma membrane] (R-HSA-1177530) p-6Y-EGFR A289D [plasma membrane] (R-HSA-1996340) p-6Y-EGFR G719A [plasma membrane] (R-HSA-1177528) EGFR L858R;T790M [plasma membrane] (R-HSA-1181386) EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1181399) EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996322) EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996325) EGFR M766_A767insASV [plasma membrane] (R-HSA-1996326) EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996317) EGFR L858R [plasma membrane] (R-HSA-1173212) EGFR G719S [plasma membrane] (R-HSA-1169418) EGFR E746_A750del [plasma membrane] (R-HSA-1181211) EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228010) EGFR A289V [plasma membrane] (R-HSA-1996321) EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228012) EGFR L747_T751del [plasma membrane] (R-HSA-1228015) EGFR A289D [plasma membrane] (R-HSA-1996327) EGFR L861Q [plasma membrane] (R-HSA-1177542) EGFR R108K [plasma membrane] (R-HSA-1996330) EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228034) EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228031) EGFR G719A [plasma membrane] (R-HSA-1177532) EGFR A289T [plasma membrane] (R-HSA-1996306) EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228025) EGFR G719C [plasma membrane] (R-HSA-1177531) EGFR T263P [plasma membrane] (R-HSA-1996315) EGFR G598V [plasma membrane] (R-HSA-1996314) EGFR L747_S752del [plasma membrane] (R-HSA-1228016) EGFR [endosome membrane] (R-HSA-9611160) p-4Y-EGFR [plasma membrane] (R-HSA-180287) p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR [plasma membrane] (R-HSA-8864019) p-Y1086,Y1101-EGFR [plasma membrane] (R-HSA-179868) EGFR [plasma membrane] (R-HSA-179837) p-6Y-EGFR [plasma membrane] (R-HSA-179803)	0.553	2

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