Phosphorylated AMPK binds AMP

Stable Identifier
R-HSA-380930
Type
Reaction
Species
Homo sapiens
Compartment
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If AMP:ATP ratio rises, AMP (instead of ATP) is bound by the AMPK-gamma subunit, which inhibits the dephosphorylation of the AMPK-alpha subunit resulting in activation of AMPK. It is not clear, as of yet, whether AMP binds to unphosphorylated AMPK.

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Orthologous Events
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