Reactome: A Curated Pathway Database

Formation of PPARG:RXRA heterodimer (ARF6 complex)

Stable Identifier
R-HSA-381262
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

PPARG binds the Retinoic acid X Receptor RXRA to form a heterodimer that has transcriptional acivation activity. The complex was initially called ARF6 when discovered. PPARG binds RXRA via the C-terminus and AF-2 regions of PPARG.

Literature References
Participants
Participant Of
Orthologous Events