Reactome | CEBPA [nucleoplasm]

CEBPA [nucleoplasm]

Stable Identifier

R-HSA-381289

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CCAAT/enhancer-binding protein alpha, CEBPA_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:P09874

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External Reference Information

External Reference

UniProt:P49715 CEBPA

Gene Names

CEBPA, CEBP

Chain

chain:1-358

Reference Genes

BioGPS Gene:1050 CEBPA

COSMIC (genes):CEBPA CEBPA

CTD Gene:1050 CEBPA

dbSNP Gene:1050 CEBPA

ENSEMBL:ENSG00000245848 CEBPA

ENSEMBL_homo_sapiens_GENE:ENSG00000245848.3 CEBPA

HGNC:1833 CEBPA

KEGG Gene (Homo sapiens):1050 CEBPA

Monarch:1050 CEBPA

NCBI Gene:1050 CEBPA

OMIM:116897 CEBPA

UCSC:P49715 CEBPA

Reference Transcript

Other Identifiers

1050

11726294_s_at

16871235

204039_PM_at

204039_at

32550_r_at

3858994

3858995

3858996

3858997

3858998

3858999

3859000

3859001

3859002

3859003

3859004

61119_at

8036004

A_23_P375494

A_24_P216165

A_24_P224727

GE60289

GO:0000050

GO:0000122

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001228

GO:0001889

GO:0001892

GO:0002070

GO:0002376

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005694

GO:0005730

GO:0006091

GO:0006351

GO:0006355

GO:0006357

GO:0006629

GO:0006954

GO:0007005

GO:0007219

GO:0008203

GO:0008283

GO:0008285

GO:0010628

GO:0019221

GO:0019900

GO:0023052

GO:0030099

GO:0030154

GO:0030163

GO:0030225

GO:0030324

GO:0030851

GO:0031490

GO:0032436

GO:0036211

GO:0036488

GO:0042127

GO:0042593

GO:0042802

GO:0042803

GO:0043032

GO:0043226

GO:0043231

GO:0043565

GO:0045444

GO:0045600

GO:0045669

GO:0045736

GO:0045786

GO:0045892

GO:0045893

GO:0045944

GO:0048839

GO:0048856

GO:0050729

GO:0050872

GO:0050873

GO:0055088

GO:0061629

GO:0070102

GO:0071285

GO:0071356

GO:0071407

GO:0071425

GO:0071941

GO:0090575

GO:0097677

GO:0140110

GO:0140297

GO:0140467

GO:1902034

GO:1990647

HMNXSV003010716

ILMN_1715715

PH_hs_0004394

TC19001396.hg

TC19002442.hg

U34070_s_at

Participates

as an output of

as an input of

as a component of

This entity regulates

Positively

Inferred To

c/ebpa [nucleoplasm] (Danio rerio)

CEBPA [nucleoplasm] (Gallus gallus)

CEBPA [nucleoplasm] (Sus scrofa)

Cebpa [nucleoplasm] (Mus musculus)

Cebpa [nucleoplasm] (Rattus norvegicus)

Mabi [nucleoplasm] (Drosophila melanogaster)

slbo [nucleoplasm] (Drosophila melanogaster)

Homologues of CEBPA [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_001274353.1, NP_004355.2, NP_001272758.1, NP_001274364.1

OpenTargets

ENSG00000245848

GeneCards

P49715

HPA

ENSG00000245848-CEBPA

Ensembl

ENSG00000245848, ENSP00000427514, ENST00000498907

PRO

P49715

Pharos - Targets

P49715

Orphanet

19235

PDB

6DC0

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P18848 ATF4	2	ATF4 [cytosol] (R-HSA-381084) ATF4 [nucleoplasm] (R-HSA-381016)	0.623	4
UniProt:P53567 CEBPG	1	CEBPG [nucleoplasm] (R-HSA-9644320)	0.623	4
UniProt:P49715 CEBPA	1	CEBPA [nucleoplasm] (R-HSA-381289)	0.623	2
UniProt:Q16520 BATF	1	BATF [nucleoplasm] (R-HSA-6789925)	0.623	3
UniProt:Q9Y2D1 ATF5	1	ATF5 [nucleoplasm] (R-HSA-9653719)	0.623	2
UniProt:P35638 DDIT3	1	DDIT3 [nucleoplasm] (R-HSA-381110)	0.623	4
UniProt:P06422 VE2			0.602	4
UniProt:P47902 CDX1			0.581	3
UniProt:P24001-2 IL32			0.576	7
UniProt:P03122 VE2			0.544	2
UniProt:P09874 PARP1	4	polySUMO2,3-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551617) monoSUMO1-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551686) PAR-PARP1 [nucleoplasm] (R-HSA-5651713) PARP1 [nucleoplasm] (R-HSA-201568)	0.499	2

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