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PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm]
Stable Identifier
R-HSA-381367
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Transcriptional regulation of white adipocyte differentiation (Homo sapiens)
Expression of ANGPTL4 (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of Adiponectin (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of CD36 (platelet glycoprotein IV, FAT) (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of CEBPA (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of FABP4 (aP2) (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of Leptin (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of Lipoprotein lipase (LPL) (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of Perilipin (PLIN) (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
PPARG:RXRA heterodimer binds to fatty acid-like ligands (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Regulation of lipid metabolism by PPARalpha (Homo sapiens)
PPARA activates gene expression (Homo sapiens)
Expression of ANGPTL4 (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Expression of CD36 (platelet glycoprotein IV, FAT) (Homo sapiens)
PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
Participants
components
Activated PPARG:RXRA [nucleoplasm] (Homo sapiens)
CREBBP [nucleoplasm] (Homo sapiens)
EP300 [nucleoplasm] (Homo sapiens)
FAM120B [nucleoplasm] (Homo sapiens)
HELZ2 [nucleoplasm] (Homo sapiens)
Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
NCOA1 [nucleoplasm] (Homo sapiens)
NCOA2 [nucleoplasm] (Homo sapiens)
NCOA3 [nucleoplasm] (Homo sapiens)
PPARGC1A [nucleoplasm] (Homo sapiens)
THRAP3 [nucleoplasm] (Homo sapiens)
Participant Of
output
PPARG:RXRA heterodimer binds to fatty acid-like ligands
This entity regulates
Negatively
Expression of Leptin
Positively
Expression of FABP4 (aP2)
Expression of Lipoprotein lipase (LPL)
Expression of ANGPTL4
Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
Expression of CD36 (platelet glycoprotein IV, FAT)
Expression of Perilipin (PLIN)
Expression of CEBPA
Expression of Adiponectin
Inferred From
Pparg:Fatty Acid:Rxra:Mediator:coactivator Complex [nucleoplasm] (Mus musculus)
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