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PEX3 [peroxisomal membrane]
Stable Identifier
R-HSA-382608
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal membrane
Synonyms
Peroxisomal biogenesis factor 3
Icon
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Class I peroxisomal membrane protein import (Homo sapiens)
PEX16:PEX19:PEX3 dissociates (Homo sapiens)
PEX3 [peroxisomal membrane] (Homo sapiens)
PEX19:class I PMP binds PEX3 (Homo sapiens)
PEX3 [peroxisomal membrane] (Homo sapiens)
PEX3:PEX19:class I PMP [peroxisomal membrane] (Homo sapiens)
PEX3 [peroxisomal membrane] (Homo sapiens)
PEX3:PEX19:class I PMP dissociates (Homo sapiens)
PEX3 [peroxisomal membrane] (Homo sapiens)
PEX3:PEX19:class I PMP [peroxisomal membrane] (Homo sapiens)
PEX3 [peroxisomal membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
ABC transporters in lipid homeostasis (Homo sapiens)
PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Homo sapiens)
PEX3 [peroxisomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P56589 PEX3
Gene Names
PEX3
Chain
chain:1-373
Reference Genes
BioGPS Gene:8504 PEX3
COSMIC (genes):PEX3 PEX3
CTD Gene:8504 PEX3
dbSNP Gene:8504 PEX3
ENSEMBL:ENSG00000034693 PEX3
HGNC:8858 PEX3
KEGG:hsa:8504 PEX3
Monarch:8504 PEX3
NCBI Gene:8504 PEX3
OMIM:603164 PEX3
UCSC:P56589 PEX3
Reference Transcript
RefSeq:NM_003630.2 PEX3
Other Identifiers
11726642_a_at
11726643_at
11726644_at
11749361_a_at
17013197
203970_PM_s_at
203970_s_at
203972_PM_s_at
203972_s_at
2875959
2928875
2928876
2928877
2928879
2928880
2928881
2928883
2928884
2928885
2928887
2928890
2928892
2928897
2928901
2928902
2928903
2928904
2928905
2928906
2928907
2928909
36864_at
4008075
8122409
8504
A_14_P120921
A_23_P259328
A_24_P320597
A_33_P3243588
GE62092
GE84301
GO:0005515
GO:0005654
GO:0005777
GO:0005778
GO:0005783
GO:0006886
GO:0007031
GO:0008289
GO:0016020
GO:0030674
GO:0032991
GO:0032994
GO:0043226
GO:0045046
GO:0060090
HMNXSV003010984
ILMN_2057389
PH_hs_0000748
TC06001052.hg
g4505726_3p_a_at
g8926848_3p_a_at
p14746
Participates
as an output of
PEX16:PEX19:PEX3 dissociates (Homo sapiens)
PEX3:PEX19:class I PMP dissociates (Homo sapiens)
PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Homo sapiens)
as a component of
PEX3:PEX19:class I PMP [peroxisomal membrane] (Homo sapiens)
as an input of
PEX19:class I PMP binds PEX3 (Homo sapiens)
PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Homo sapiens)
Other forms of this molecule
PEX3 [cytosol]
Inferred To
prx-3 [peroxisomal membrane]
(Caenorhabditis elegans)
Pex3 [peroxisomal membrane]
(Drosophila melanogaster)
Pex3 [peroxisomal membrane]
(Mus musculus)
Pex3 [peroxisomal membrane]
(Rattus norvegicus)
pex3 [peroxisomal membrane]
(Danio rerio)
pex3 [peroxisomal membrane]
(Dictyostelium discoideum)
pex3 [peroxisomal membrane]
(Xenopus tropicalis)
PEX3 [peroxisomal membrane]
(Bos taurus)
PEX3 [peroxisomal membrane]
(Canis familiaris)
PEX3 [peroxisomal membrane]
(Gallus gallus)
PEX3 [peroxisomal membrane]
(Saccharomyces cerevisiae)
PEX3 [peroxisomal membrane]
(Schizosaccharomyces pombe)
PEX3 [peroxisomal membrane]
(Sus scrofa)
Cross References
RefSeq
NP_003621.1
ENSEMBL
ENST00000367591
,
ENSP00000356563
OpenTargets
ENSG00000034693
HPA
ENSG00000034693-PEX3
PRO
P56589
Pharos - Targets
P56589
GlyGen
P56589
Orphanet
PEX3
PDB
3AJB
,
3MK4
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P40855 PEX19
1
PEX19 [cytosol]
(R-HSA-3009036)
0.982
60
UniProt:Q9Y5Y5 PEX16
2
PEX16 [peroxisomal membrane]
(R-HSA-9603805)
PEX16 [cytosol]
(R-HSA-9603790)
0.752
6
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