Vasopressin-like receptors

Stable Identifier
R-HSA-388479
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Pathway
Species
Homo sapiens
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The vasopressins are peptide hormones consisting of nine amino acids (nonapeptides). They include arginine vasopressin (AVP; anti-diuretic hormone, ADH) and oxytocin. They are synthesized in the hypothalamus from a precursor and released from stores in the posterior pituitary into the blood stream. One of the most important roles of vasopressins is the regulation of water retention in the body. Oxytocin is important in uterine contraction during birth. The vasopressins act via AVP and oxytocin receptors. These are connected to G proteins which act as second messengers and convey the signal inside the cell.

Literature References
PubMed ID Title Journal Year
8734452 Vasopressin and oxytocin receptors

Zingg, HH

Baillieres Clin Endocrinol Metab 1996
8719042 Molecular neurobiology and pharmacology of the vasopressin/oxytocin receptor family

Peter, J, Burbach, H, Adan, RA, Lolait, SJ, van Leeuwen, FW, Mezey, E, Palkovits, M, Barberis, C

Cell Mol Neurobiol 1995
11274341 The oxytocin receptor system: structure, function, and regulation

Gimpl, G, Fahrenholz, F

Physiol Rev 2001
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