MC2R (aka ACTH receptor) selectively binds POMC(138-176) (ACTH, corticotropin) (Gantz et al. 1993, Lee et al. 1961, Mountjoy et al. 1992). ACTH regulates adrenal cortical function via the G protein alpha-s subunit.
Robbins, LS, Cone, RD, Mortrud, MT, Mountjoy, KG
Gantz, I, Yamada, T, Shimoto, Y, Miwa, H, Tashiro, T, Konda, Y, Munzert, G, Watson, SJ, DelValle, J
Lerner, AB, Buettner-Janusch, V, Lee, TH
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