ICOS binds ICOSL/B7-H2

Stable Identifier
R-HSA-388817
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Inducible T cell co-stimulatory (ICOS) protein is the third member of the CD28 family that regulates T-cell activation and function. ICOS interacts with B7H2 (ICOSL, B7RP-1), a member of the B7 family expressed on the antigen-presenting cell.

Literature References
PubMed ID Title Journal Year
15007255 ICOS: a new costimulatory ligand/receptor pair and its role in T-cell activion

Richter, G, Burdach, S

Onkologie 2004
15870016 Regulation of immune and autoimmune responses by ICOS-B7h interaction

Nurieva, RI

Clin Immunol 2005
Participants
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Orthologous Events
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